单纯疱疹病毒性角膜炎复发及治疗的研究进展  

Research progress on recurrence and treatment of herpes simplex keratitis

作　　者：孙婉彤 张红[1] Wan-Tong Sun;Hong Zhang(Eye Hospital, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China)

机构地区：[1]哈尔滨医科大学附属第一医院眼科分院,中国黑龙江省哈尔滨市150001

出　　处：《国际眼科杂志》2019年第3期384-387,共4页International Eye Science

基　　金：国家自然科学基金资助项目(No.81671844)~~

摘　　要：单纯疱疹病毒性角膜炎(herpes simplex keratitis,HSK)是由单纯疱疹病毒(HSV)引起的一种严重的感染性角膜疾病。HSV的感染有两种形式:原发性感染和复发性感染。其中,复发性HSV感染的相关机制和干预方式是近些年来的研究焦点。本文介绍了几种常见的HSK的复发免疫机制及治疗,分析了最新研究发现的各种抗HSV复发的药物,希望能尽早开发出新型的干预方式,开发出具有较强疗效和较小毒性的化合物,使其减少潜在的副作用,提供更好的治疗效果。·Herpes simplex viral keratitis(HSK)is caused by herpes simplex virus a serious infective corneal disease.Herpes simplex virus(HSV)infection comes in two forms:primary and recurrent.Between them,the recurrent herpes simplex virus infection way of relevant mechanisms and intervention is the research focus in recent years.In this article,we’ve introduced the recurrent immune system and treatment of the recurrent herpes of herpes simplex,analysed the newly discovered drugs against herpes simplex virus recurrence,and we’re hoping to develop a new form of intervention,a chemical that has a stronger effect and less toxic,so that we can reduce the potential side effects and provide better treatment results.

关 键 词：单纯疱疹病毒性角膜炎 发病机制 干预方式 复发 感染性眼部疾病 

分 类 号：R772.21[医药卫生—眼科]