镍铬合金义齿在人工唾液中镍离子析出行为的研究  

Study on the Precipitation Behavior of Nickel Ion from Nickel-ChromiumAlloy Crowns in Artificial Saliva

作　　者：姜红强 甄辉 寇艳芹 陈宁清 郑超 谢昕 JIANG Hongqiang;ZHEN Hui;KOU Yanqin;CHEN Ningqing;ZHENG Chao;XIE Xin(Zhejiang Medical Device Evaluation Center,Hangzhou Zhejiang 310009,China)

机构地区：[1]浙江省医疗器械审评中心,浙江杭州310009

出　　处：《中国医疗设备》2019年第3期54-57,共4页China Medical Devices

基　　金：浙江省食品药品监管系统科技计划项目(YQ201701)

摘　　要：目的对镍铬烤瓷冠以及不同铬含量的镍铬金属冠在人工唾液中镍离子的析出行为进行研究。方法将镍铬烤瓷冠以及不同铬含量的镍铬金属冠分别浸泡在pH6.8恒温(37±1)℃的人工唾液环境中,每隔一周将试样取出采用火焰原子吸收光谱法测试镍离子的析出量。结果高铬组金属冠镍离子的析出速率随着时间的推移逐渐增加,于第2周达到高峰,之后逐渐下降;而低铬组在测试周期内(7周),镍离子的析出速率呈持续缓慢上升趋势;与镍铬金属冠相比,镍铬烤瓷冠镍离子的析出量显著降低。结论高铬金属冠具有耐腐蚀性,而镍铬烤瓷冠具有更好的生物安全性。Objective To study the nickel ion precipitation behavior of Nickel-Chromium (Ni-Cr) alloy ceramic crowns and Ni-Cr alloy metal crowns with different Cr content in artificial saliva. Methods Ni-Cr alloy ceramic crowns and Ni-Cr alloy metal crowns with different Cr content were immersed in the artificial saliva under pH6.8 at a constant temperature (37±1)℃. The samples were taken out every other week, and the concentration of nickel ion was tested by flame atomic absorption spectrometry. Results The nickel ion precipitation rate of Ni-Cr alloy metal crowns with high Cr content increased gradually with time, and reached a peak at the second week, then decreased gradually. While the precipitation rate of nickel ions kept increasing slowly during the test period (7 weeks) in the low Cr content group. Compared with Ni-Cr alloy metal crowns, the amount of nickel ion released from Ni-Cr alloy ceramic crowns decreased significantly. Conclusion The high Cr metal crown has corrosion resistance, while the Ni-Cr ceramic crown has better biological safety.

关 键 词：镍铬金属冠 镍铬烤瓷冠 镍离子 人工唾液 

分 类 号：R783.1[医药卫生—口腔医学]