Novel Cancer Treatment Using Targeted Delivery of Short-Lived Radiologically Activated Nanoparticles  

作　　者：P.L.Andrade J.B.Leao 

机构地区：[1]Núcleo de Engenharias, Centro Universitário Boa Viagem, Wyden, Recife-PE 51200-060, Brazil [2]NIST Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA

出　　处：《Journal of Health Science》2019年第1期43-47,共5页健康科学（英文版）

摘　　要：The goal of our preliminary study is to show that a minimal of overall body toxicity while maximizing the cancer tumor treatment may be achieved in a novel approach where minute amounts of coated nanoparticles may be radiologically activated prior to treatment and“coerce”tumor cells into readily absorb these nanoparticles.This targeted intracytoplasmic delivery of short-lived radiologically activated nanoparticles could provide less“whole-body”radiation dose while delivering a short lived potent tumor localized dose,along with their low toxicity may prove to be another tool in the treatment of diverse cancers.

关 键 词：NANOPARTICLES neutron activation IRRADIATION cancer METABOLISM WARBURG effect GLUTAMINE GLUCOSE 

分 类 号：Q[生物学]