复发性脑梗死危险因素及与动脉狭窄的相关性  

Risk factors of recurrent ischemic stroke and its correlation with arterial stenosis

作　　者：李克伟 黎红华 LI Kewei;LI Honghua(Hubei University of Chinese Medicine,Wuhan 430065,China;Department of Neurology,Central Theater Command General Hospital of the Chinese People's Liberation Army,Wuhan 430070,China)

机构地区：[1]湖北中医药大学,湖北武汉430065 [2]中国人民解放军中部战区总医院神经内科,湖北武汉430070

出　　处：《中国实用神经疾病杂志》2019年第1期23-27,共5页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨复发性脑梗死的危险因素及与颅内动脉粥样硬化性狭窄(ICAS)、颅外动脉粥样硬化性狭窄(ECAS)的相关性。方法收集2017-08—2018-08就诊于中国人民解放军中部战区总医院的急性脑梗死患者132例,均行320排CT血管成像(CTA)检查,根据既往有无脑梗死史分为复发组(57例)及初发组(75例),分析复发性脑梗死的危险因素及与颅内外动脉粥样硬化性狭窄的相关性。结果单因素分析显示,年龄、甘油三酯(TG)等差异有统计学意义(P<0.05);ECAS、颅内外动脉狭窄程度、ICAS等组间差异有统计学意义(P<0.05或0.01)。多因素非条件Logistic回归分析显示,TG是复发性脑梗死的独立危险因素。结论脑梗死的复发受年龄、TG、ICAS、ECAS、颅内外动脉狭窄程度等多种因素影响,其中TG是其独立危险因素。通过控制相关危险因素,积极预防颅内外动脉粥样硬化,将有利于降低脑梗死的复发风险。Objective To explore the risk factors of recurrent ischemic stroke and its correlation with intracranial artery stenosis(ICAS)and extracranial artery stenosis(ECAS).Methods In this study,a total of 132 patiens with recurrent ischemic stroke were enrolled from August 2017 to August 2018 in authors'hospital.All the patients were examined by 320 rows of CT angiography(CTA).According to the patients'previous history of ischemic stroke,they were divided into recurrent group(57 cases)and primary group(75 cases).The risk factors of recurrent ischemic stroke and its correlation with intracranial artery stenosis(ICAS)and extracranial artery stenosis(ECAS)were statistically analyzed.Results Univariate analysis between the two groups showed statistically significant differences in age,triglyceride(TG)and other factors(P<0.05).Univariate analysis between the two groups showed statistically significant differences in ECAS,degree of ICAS and degree of ECAS(P<0.05).The difference in ICAS between the two groups was statistically significant(P<0.01).Multivariate non conditional Logistic regression analysis showed that TG was an independent risk factor for recurrent ischemic stroke.Conclusion The recurrence of ischemic stroke is affected by many factors such as theage,TG,ICAS,ECAS,degree of ICAS and degree of ECAS,among which TG is an independent risk factor.By controlling related risk factors,active prevention of atherosclerotic stenosis will be conducive to reducing the recurrence risk of ischemic stroke.

关 键 词：复发性脑梗死 动脉粥样硬化 动脉狭窄 甘油三酯 危险因素 CT血管成像 LOGISTIC回归分析 

分 类 号：R743.33[医药卫生—神经病学与精神病学]