腰交感神经阻滞联合盐酸沙格雷酯治疗下肢CRPS-Ⅰ型  

Combination of the Lumbar Sympathetic Nerve Block and Sarpogrelate Hydrochloride in the Treatment of Lower Extremity CRPS-I

作　　者：熊志宏[1] Xiong Zhihong(Department of Pain Medicine, The Second People's Hospital of Yunnan Province, Kunming 650021, China)

机构地区：[1]云南省第二人民医院疼痛科,昆明650021

出　　处：《大理大学学报》2019年第2期49-51,共3页Journal of Dali University

摘　　要：目的:观察腰交感神经阻滞联合盐酸沙格雷酯治疗下肢复杂性局部疼痛综合征(CRPS)的临床效果。方法:将下肢CRPS-Ⅰ型152例,随机分为Ⅰ、Ⅱ两组,每组76例。Ⅰ组行单纯腰交感神经阻滞治疗,Ⅱ组行腰交感神经阻滞联合盐酸沙格雷酯治疗。在治疗前、治疗后1个月及6个月对疼痛视觉模拟评分及疗效评定进行评价。结果:治疗后1个月和治疗后6个月观察,两组比较症状改善程度与有效率差异均有统计学意义(P<0.05)。两组均无并发症发生。结论:腰交感神经阻滞联合盐酸沙格雷酯对下肢CRPS-Ⅰ型的患者起到有效缓解疼痛和痛觉过敏,改善下肢乏力、冰冷、发汗障碍等营养不良症状,是CRPS-Ⅰ型患者的一种有效治疗方法。Objective: To observe the clinical effect of the combination of the lumbar sympathetic nerve block and sarpogrelate hydrochloride in the treatment of patients with complex regional pain syndrome(CRPS)of lower limbs. Methods: 152 patients with CRPS type Ⅰ were randomly divided into group Ⅰ and group Ⅱ, 76 cases in each group. Patients in group Ⅰ were treated simply with lumbar sympathetic nerve block, while patients in group Ⅱ were treated with lumbar sympathetic nerve block combined with sarpogrelate hydrochloride. The visual analogue scores(VAS)and efficacy of the two groups were evaluated before and after treatment for 1 and 6 months. Results: There was significant difference in the improvement of symptoms and efficiency between before and after treatment for 1 and 6 months of treatment(P<0.05)in the two groups. No complications occurred in both groups. Conclusion: Lumbar sympathetic nerve block combined with sarpogrelate hydrochloride for CRPS-Ⅰ of lower limbs relieves pain and hyperalgesia, improves malnutrition symptoms in lower limbs such as weakness, ice-cold, sweating disorder. It is an effective treatment method for patients with CRPS-Ⅰ.

关 键 词：复杂性局部疼痛综合征 腰交感神经阻滞 盐酸沙格雷酯 

分 类 号：R741.05[医药卫生—神经病学与精神病学]