“蔗糖八乙酸酯的制备”综合性有机化学实验设计  

Design on Comprehensive Organic Chemistry Experiment of Preparation of Sucrose Octaacetate

作　　者：邱华[1] 顾军渭[1] 史学涛 陈芳[1] 李君 管萍[1] QIU Hua;GU Jun-wei;SHI Xue-tao;CHEN Fang;LI Jun;GUAN Ping(Department of Applied Chemistry,School of Science,Northwestern Polytechnical University,Xi ’ an 710072,China)

机构地区：[1]西北工业大学理学院应用化学系,西安710072

出　　处：《南昌航空大学学报（自然科学版）》2018年第4期111-116,共6页Journal of Nanchang Hangkong University(Natural Sciences)

基　　金：西北工业大学2018年教学与考核模式改革课程资助项目;西北工业大学2018年实验核心课程建设资助项目

摘　　要：在有机化学实验课程中,通常忽略了生命科学和日常生活中最常见的碳水化合物有关的实验内容。"蔗糖八乙酸酯的制备"综合性实验的设计,弥补了这一不足,而且该实验具有原料易得、操作简便、产物产率高的特点。通过蔗糖八乙酸酯的合成和重结晶分离提纯,并进行红外、核磁、质谱和熔点测定对产物进行结构表征,形成一个完整的、系统的实验过程,不仅有效地提高学生们的动手能力、谱图分析和解析能力,还利于学生综合实验能力和科学素养的培养。With the development of life science and technology,carbohydrates in organic chemistry courses should be paid more attention. But in most of the organic chemistry experiment courses in domestic colleges and universities,the experiments about carbohydrates are usually neglected.“Preparation of surcrose octaacetate” as a comprehensive experiment is designed to make up for this deficiency,including synthesis of sucrose octaacetate,purification through recrystallization process,and characterizations by Fourier transform infrared spectrometer (FI-IR),Proton nuclear magnetic resonance (1H NMR),mass spectrometry (MS) and melting point determination. Through the systematic and complete comprehensive design of the experiment,it not only enables students to master the basic unit operation,but also the analysis of the structure of organic compounds,which is beneficial to train the students’ comprehensive experimental ability and scientific literacy.

关 键 词：实验教学 综合性实验设计 有机化学实验 蔗糖八乙酸酯 

分 类 号：G642.423[文化科学—高等教育学]