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作 者:李晓保 邬兰[1] 王阅春[1] 赵德路 朱有家[1] 王翠霞 LI Xiao-bao;WU Lan;WANG Yue-chun;ZHAO De-lu;ZHU You-jia;WANG Cui-xia(Department of Stomatology, Zhongnan Hospital of Wuhan University, Hubei Province, Wuhan 430071, China;Department of Stomatology, Puren Hospital of Wuhan City, Hubei Province, Wuhan 430081, China)
机构地区:[1]武汉大学中南医院口腔科,湖北武汉430071 [2]武汉市普仁医院口腔科,湖北武汉430081
出 处:《中国当代医药》2019年第7期8-12,共5页China Modern Medicine
基 金:湖北省自然科学基金项目(2017CFB776)
摘 要:目的对预防腮腺肿瘤切除术后并发症的Meta分析进行汇总评价。方法检索PubMed、Cochrane Library、CNKI和WanFang Data关于腮腺肿瘤切除术后并发症预防的Meta分析,检索时间为建库到2018年9月12日。按照纳入标准筛选文献、提取资料,采用AMSTAR量表评价纳入研究的质量。结果共纳入24个研究,探讨13种干预措施对预防腮腺肿瘤切除术后并发症的效果。AMSTAR质量评价结果显示,3个高质量研究,16个中等质量研究,5个低质量研究。结论本研究所涉及的干预措施对Frey综合征、涎瘘/积液、面部畸形预防有一定的效果,对术后复发、感染无明显效果,对面神经麻痹的疗效不确定;此外,仍然需实施严谨和规范的原始研究、直接比较Meta分析/系统评价或间接比较网状Meta分析,为临床提供更可靠、全面的证据。Objective To systematically evaluate the meta-analysis for prevention of postoperative complications after parotid gland tumor resection. Methods Meta-analysis of for prevention of postoperative complications after parotid gland tumor resection was retrieved from PubMed, Cochrane Library, CNKI and WanFang Data. The search time was from building database to September 12, 2018. According to the inclusion criteria, literature was screened and data were extracted. The quality of inclusion study was evaluated by AMSTAR scale. Results A total of 24 studies were included to investigate the effects of 13 interventions on the prevention of complications after parotid gland tumor resection. The AMSTAR quality evaluation results showed 3 studies were high quality, 16 studies were moderate quality, and 5 studies were low quality. Conclusion The interventions involved in this study have certain effects on the prevention of Frey syndrome, salivary fistula/effusion, and facial deformity. There is no obvious effect on postoperative recurrence or infection, and the effect on facial nerve palsy is uncertain. In addition, there is still a need for rigorous and standardized original research, direct comparative meta-analysis/systematic evaluation or indirect comparative mesh meta-analysis to provides more reliable and comprehensive evidence for clinic.
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