食用土当归有机酸成分的抑菌性研究  

Antimicrobial activity of organic acids from root of Aralia cordata Thunb

作　　者：党凯茹 彭腾[1] 邹和平 陈思敏[1] 韩笑[1] 匡宇[1] 赵永艳 DANG Kai-ru;PENG Teng;ZOU He-ping;CHEN Si-min;HAN Xiao;KUANG Yu;ZHAO Yong-yan(School of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,Sichuan)

机构地区：[1]成都中医药大学药学院,四川成都610075 [2]Chongqing Taiji Group,Chongqing 401120

出　　处：《中药与临床》2018年第3期37-40,共4页Pharmacy and Clinics of Chinese Materia Medica

基　　金：四川省科技支撑计划(No.2011SC0235);国家科技支撑计划(No.2015BAC05B02);成都中医药大学校基金(CGZH1706);四川省青年科技创新研究团队专项计划(N0.2016TD0006)

摘　　要：目的:研究食用土当归有机酸成分的抑菌性。方法:以食用土当归为试材,采用牛筋杯法对其提取物贝壳杉烯酸、海松酸和总有机酸的抑菌活性进行初步研究。结果:贝壳杉烯酸、海松酸、总有机酸对6种细菌均表现出一定的抑制作用;铜绿假单胞菌中抑菌圈直径大于大肠埃希菌、金色葡萄球菌、阴沟肠杆菌、肺炎克雷伯菌和表皮葡萄球菌抑菌圈的直径。结论:食用土当归有机酸成分具有一定的抑菌活性,对铜绿假单胞菌的抑菌作用更为明显。Objective:To investigate antibacterial activities of organic acids from roots of Aralia cordata Thunb.Method:The antibacterial activities of kaurenic acid,pimaric acid and total organic acids which from roots of Aralia cordata Thunb.were preliminarily evaluated by beef tendon cup method.Result:Kaurenic acid,pimaric acid and total organic acids all had a certain inhibitory effect on six bacteria.The inhibition zone of pseudomonas aeruginosa was greater than that of escherichia coli,staphylococcus aureus,enterobacter cloacae,klebsiella pneumoniae and staphylococcus epidermidis.Conclusion:The organic acids from roots of Aralia cordata Thunb.have good antimicrobial activities,especially on pseudomonas aeruginosa.

关 键 词：食用土当归 贝壳杉烯酸 海松酸 抑菌性 

分 类 号：R285.5[医药卫生—中药学]