首发精神障碍的抗NMDAR脑炎与精神分裂症的鉴别  

Identification of anti-NMDA receptor encephalitis in first-episode mental disorders and schizophrenia

作　　者：关念红[1] Guan Nianhong(Department of Psychiatry, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China)

机构地区：[1]中山大学附属第三医院精神心理科,广州510630

出　　处：《中国医师杂志》2019年第2期164-166,共3页Journal of Chinese Physician

基　　金：广东省科学技术厅基金(2014A020212721)~~

摘　　要：精神症状是抗N-甲基-D-天门冬氨酸(NMDA)受体脑炎患者最常见的症状之一,与精神分裂症的症状相比没有特异性。既往无精神障碍史的年轻女性患者急骤出现精神症状,有意识障碍或可疑意识障碍,特别是有紧张症时,需要进行脑电图及头部磁共振检查进行抗NMDA受体脑炎的鉴别。脑脊液NMDA受体抗体异常是确诊依据。Psychiatric symptoms are one of the most common symptoms in patients with anti-N-methyl-D-aspartate (NMDA) receptor encephalitis, which is not specific compared with the symptoms of schizophrenia. Young female patients without previous history of mental disorders have sudden onset of psychiatric symptoms, conscious disturbances or suspicious conscious disturbances, especially in the presence of catatonic, requiring electroencephalogram (EEG) and head magnetic resonance imaging for the identification of anti-NMDA receptor encephalitis. Abnormal NMDA receptor antibody in cerebrospinal fluid is the basis of diagnosis.

关 键 词：精神障碍 抗N-甲基-D-天冬氨酸受体脑炎 精神分裂症 诊断 鉴别 

分 类 号：R742.9[医药卫生—神经病学与精神病学] R749.3[医药卫生—临床医学]