氟化钠护齿剂在预防学龄前儿童乳牙龋齿中的疗效观察  

The effect of fluoride varnish Duraphat in preventing deciduous dental caries in preschool children

作　　者：苏红如[1] 杨忍忍 钱文昊[1] 余金明 SU Hongru;YANG Ren-ren;QIAN Wen-hao;YU Jin-ming(Dental Disease Control Institute,Xuhui District. Shanghai200032;Key Laboratory of Health Technology Assessment of Ministry of Health,Collaborative Innovation Center ofSocial Risks Governance in Health,School of Public Health,Fudan University. Shanghai 200032,China)

机构地区：[1]上海市徐汇区牙病防治所,上海200032 [2]复旦大学公共卫生学院卫生部卫生技术评估重点实验室国民健康社会风险预警协同创新中心,上海200032

出　　处：《上海口腔医学》2019年第1期48-52,共5页Shanghai Journal of Stomatology

基　　金：上海市徐汇区卫生尖峰学科(SHXH201706)

摘　　要：目的 :观察氟化钠护齿剂预防儿童乳牙龋齿的效果,为全面开展学龄前儿童涂氟防龋提供依据。方法 :采取随机整群抽样方法,在上海市徐汇区抽取25所公办幼儿园3～4岁小班儿童共1140名作为研究对象,在儿童家长知情同意的情况下,本着自愿原则,将研究对象分为2组。涂氟组762名,每半年涂氟1次,连续2年共涂布4次;对照组378名,不做涂氟处理。对所有入组儿童进行口腔卫生指导,比较2组儿童患龋率、龋均、龋病发病率、新增龋均的情况,采用SAS 9.4软件包进行统计学分析。结果:2年后,对照组的患龋率、龋均、龋病发生率和新增龋均均显著高于涂氟组(P<0.05)。结论:在学龄前儿童中应用氟化钠护齿剂,能有效降低乳牙龋病发生率和新增龋均,值得在学龄前儿童中推广应用。PURPOSE: To evaluate the effect of fluoride varnish Duraphat on preventing caries of primary teeth caries, and provide scientific basis for the establishment of oral health care. METHODS: 1140 preschool children aged 3~4 years old were chosen from 25 public kindergartens in Xuhui district of Shanghai by cluster sampling method, they were divided into2 groups on a voluntary basis with the informed consent of the child’s parents. 762 preschool children in Fluoride Varnish group were taken oral examination and used fluoride varnishes every 6 months, 378 preschool children in the control group were without treatment. Oral health instruction was given to all the children. The data of caries prevalence, mean dmft,caries incidence and mean increments of dmft(decayed, missing and filled teeth) of 2 groups were compared. The results were analyzed using SAS 9.4 software package. RESULTS: After 2 years, caries prevalence, mean dmft, caries incidence and mean increments of dmft of fluoride varnish groups were lower than those of control group and the difference was statistically significant(P<0.05). CONCLUSIONS: Fluoride varnish Duraphat is effective in decreasing caries incidence and mean dmft increments of primary teeth in preschool children and is worthy to be used widely in Xuhui district.

关 键 词：氟化钠护齿剂 多乐氟 龋病预防 学龄前儿童 

分 类 号：R780.1[医药卫生—口腔医学]