腹腔镜子宫全切术治疗子宫良性肿瘤的临床价值  

Application value of laparoscopic hysterectomy in the treatment of benign gynecologic tumor

作　　者：王红燕 Wang Hongyan(Department of Gynecology, Houma People's Hospital, Houma 043000, China)

机构地区：[1]山西省侯马市人民医院妇科,043000

出　　处：《中国实用医刊》2019年第1期62-65,共4页Chinese Journal of Practical Medicine

摘　　要：目的探讨腹腔镜子宫全切术治疗子宫良性肿瘤的临床价值。方法选取2017年2月至2018年4月侯马市人民医院收治的74例因子宫良性肿瘤需行子宫全切术的患者,随机将其分为腹腔镜组37例(给予腹腔镜子宫全切术治疗)与开腹组37例(给予开腹子宫全切术治疗)。记录并比较两组患者的临床指标、炎症因子指标、机体免疫功能指标及术后并发症发生情况。结果腹腔镜组手术时间[(53.67±7.45)min]、术中出血量[(64.73±8.27)ml]、术后排气时间[(25.49±2.62)h]与住院时间[(5.14±1.21)d]均少于开腹组[(75.82±9.48)min、(111.51±12.93)ml、(34.61±3.18)h、(7.06±1.49)d,P<0.05];腹腔镜组术后最高体温[(37.16±0.81)℃]与开腹组[(37.43±0.77)℃]比较差异未见统计学意义(P>0.05)。治疗后3d腹腔镜组患者肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、C反应蛋白(CRP)水平降低(P<0.05)。治疗后3d,腹腔镜组患者CD4^+与CD4^+/CD8^+降低、CD8^+升高(P<0.05)。腹腔镜组术后并发症发生率为10.81%,低于开腹组的35.14%(P<0.05)。结论对妇科良性肿瘤患者术给予腹腔镜子宫全切术治疗临床效果较好,可明显抑制炎症反应并改善机体免疫功能,且术后并发症发生率较低,值得推广应用。Objective To discuss the clinical application value of laparoscopic hysterectomy in the treatment of benign gynecologic tumor. Methods Seventy-four patients with benign gynecologic tumor who were treated by hysterectomy in Houma People’s Hospital from February 2017 to April 2018 were selected, and they were randomly divided into laparoscopy group (37 cases, treated by laparoscopic hysterectomy) and the laparotomy group (37 cases, treated by laparotomy hysterectomy). The clinical indexes, inflammatory factors indexes, body immune function indexes and postoperative complications were recorded and compared between the two groups. Results The operative time (53.67±7.45)min, intraoperative bleeding (64.73±8.27)ml, postoperative exhaust time (25.49±2.62)h and hospitalization time (5.14±1.21)d of laparoscopy group were significantly less than those of laparotomy group, which was (75.82±9.48) min,(111.51±12.93) ml,(34.61±3.18)h,(7.06±1.49)d, respectively, and the difference was significant (P<0.05). But the postoperative maximum body temperature (37.16±0.81)℃ of laparoscopy group was not significantly different from the (37.43±0.77)℃ of laparotomy group (P>0.05). The tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), C reactive protein (CRP) levels of laparoscopy group 3 d after treatment were significantly decreased (P<0.05). The levels of CD4^+, CD4^+/CD8^+ decreased and CD8^+ increased in laparoscopy group (P<0.05). The incidence of postoperative complications in laparoscopy group (10.81%) was significantly lower than that of laparotomy group (35.14%), P<0.05. Conclusions The clinical effect of laparoscopic hysterectomy in the treatment of benign gynecologic tumor is better. It can obviously inhibit the inflammatory reaction and improve the body immune function, with low postoperative complications incidence, which is worthy of popularization and application.

关 键 词：腹腔镜 子宫全切术 良性肿瘤 

分 类 号：R737.33[医药卫生—肿瘤]