空腹血糖对缺血性脑卒中患者脑血管狭窄程度的影响  

Effects of fasting plasma glucose on the severity of cerebrovascular stenosis in ischemic stroke patients

作　　者：周玮 卢姗[1] 杨洁[1] 阚敬保 沈歌前 刘云[1] Zhou Wei;Lu Shan;Yang Jie;Kan Jingbao;Shen Geqian;Liu Yun(Department of Gerontology, the First Affiliated Hospital of NMU, Nanjing 210029, China)

机构地区：[1]南京医科大学第一附属医院老年医学科,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2019年第2期228-231,共4页Journal of Nanjing Medical University(Natural Sciences)

基　　金：国家重点研发计划(2018YFC1314901);国家自然科学基金青年基金(81600001);江苏省自然科学基金青年基金(BK20141026);江苏省医学重点人才(ZDRCA2016005);江苏省科技计划项目(BE2016002-4);南京市科技计划项目(201608003)

摘　　要：目的:探讨空腹血糖(fasting plasma glucose,FPG)对缺血性脑卒中患者脑血管狭窄程度的影响。方法:回顾性分析缺血性脑卒中患者307例,按FPG水平分为3组,对患者的实验室及影像学资料进行分析。结果:随着FPG增加,脑血管狭窄支数、狭窄程度均增加。年龄<60岁的患者,FPG 5.6～7.0 mmol/L组及FPG>7.0 mmol/L组的脑血管狭窄均重于FPG<5.6 mmol/L组;年龄≥60岁的患者,FPG>7.0 mmol/L组的脑血管狭窄较FPG<5.6 mmol/L组严重。结论:缺血性脑卒中患者脑血管的狭窄程度随着FPG增加而增加;<60岁的患者FPG>5.6 mmol/L或≥60岁的患者FPG>7.0 mmol/L,其脑血管的狭窄程度较同龄FPG<5.6 mmol/L者严重。Objective:To investigate the effect of fasting plasma glucose(FPG)on the severity of cerebrovascular stenosis in patients with ischemic stroke. Methods:Three hundred and seven patients with ischemic stroke were divided into three groups according to the level of FPG. The clinical features and imaging data of patients were analyzed. Results:With the increase of FPG,the number of diseased vessel,the severity of cerebrovascular stenosis were increased. In patients with age< 60 years,the cerebrovascular stenosis in FPG 5.6-7.0 mmol/L group and FPG > 7.0 mmol/L group was severe than that in FPG < 5.6 mmol/L group. And in patierts with age≥60 years the stenosis in FPG > 7.0 mmol/L group were more serious than that in FPG < 5.6 mmol/L group. Conclusion:Stenosis of cerebrovascular in ischemic stroke increased along with the increase of FPG. The vascular stenosis in patients less than 60 years old with FPG>5.6 mmol/Lorover 60 yearsoldwithFPG> 7.0 mmol/L is more serious than that in patients with FPG< 5.6 mmol/L.

关 键 词：空腹血糖 缺血性脑卒中 脑血管 年龄 

分 类 号：R743.34[医药卫生—神经病学与精神病学]