颅后窝肿瘤术后颅内感染的相关因素分析  

Analysis of factors relavant to intracranial infection after operation for posterior cranial fossa tumors

作　　者：龙飞[1] 秦坤明[1] 廖声潮[1] 唐纯海[1] 吴京展[1] 莫凯[1] 邝泓[1] 刘涛[1] Long Fei;Qin Kunming;Liao Shengchao;Tang Chunhai;Wu Jingzhan;Mo Kai;Kuang Hong;Liu Tao(Department of Neurosurgery,the Second Affiliated Hospital of Guangxi Medical University,Nanning,Guangxi 530000,China)

机构地区：[1]广西医科大学第二附属医院神经外科,南宁530000

出　　处：《中国微侵袭神经外科杂志》2018年第12期536-538,共3页Chinese Journal of Minimally Invasive Neurosurgery

基　　金：广西壮族自治区卫生厅自筹经费课题(编号:Z20170091)

摘　　要：目的探讨颅后窝肿瘤术后颅内感染的危险因素,为临床防治术后颅内感染提供依据。方法回顾性分析169例行开颅手术的颅后窝肿瘤病人的临床资料,术后颅内感染28例,未感染141例。纳入可能造成颅内感染的13项相关因素,并行单因素分析,有统计学差异者纳入Logistic多因素分析。结果术后发生颅内感染28例(16.6%),单因素分析结果显示:手术时间、留置脑室引流管、术后脑脊液漏、术中消毒液冲洗是颅后窝肿瘤术后颅内感染的影响因素(P <0.05)。多因素Logistic回归分析结果显示:留置脑室引流管、术后脑脊液漏是颅后窝肿瘤术后颅内感染的独立危险因素(P <0.05)。结论对危险因素采用相应有效的预防措施,以尽可能减少颅后窝肿瘤术后颅内感染的发生。Objective To explore the risk factors of intracranial infection after operation in posterior cranial fossa tumors for providing a basis for the prevention and treatment of intracranial infections. Methods Clinical data of 169 patients with posterior cranial fossa tumors undergoing craniotomy were analyzed retrospectively, including intracranial infection in 28 patients and non-infection in 141 after craniotomy. The 13 relative factors that may cause intracranial infection were included, then, univariate analysis was performed,and logistic multivariate analysis was performed for the factors with statistical differences. Results The intracranial infection occurred in 28 patients(16.6%) after the operation. Univariate analysis showed that surgery time, ventricle drainage, postoperative cerebrospinal fluid leakage, intraoperative irrigation by disinfectant liquid were the factors influencing intracranial infection after surgery in the posterior cranial fossa tumors(P < 0.05). Logistic regression analysis showed that ventricle drainage and postoperative cerebrospinal fluid leakage were independent risk factors(P < 0.05). Conclusion The effective preventive measures should be performed in posterior cranial fossa tumor patients with high risk factors to reduce the incidence of intracranial infection after operation.

关 键 词：脑肿瘤 颅窝 后 颅内感染 影响因素 

分 类 号：R745.11[医药卫生—神经病学与精神病学] R651.1[医药卫生—临床医学]