血栓通脉汤联合针刺治疗脑梗死及对神经、血管功能的影响  

Effect of Xueshuan Tongmai Decoction and Acupuncture in Treatment of Cerebral Thrombosis in Patients and Its Influence on Nerve Function and Vascular Function

作　　者：王丹丹[1] 薄文伟 张沛[1] 韩富红[1] 刘志辉 白杰 蔡梅芝 卢宝全[1] WANG Dandan;BO Wenwei;ZHANG Pei;HAN Fuhong;LIU Zhihui;BAI Jie;CAI Meizhi(Department of Neurology, Tangshan City Workers Hospital, Tangshan 063000 , Hebei, China;Department of Radiology , Beijing Fangshan Liangxiang Hospital, Beijing 102401 ,China)

机构地区：[1]唐山市工人医院神经内科,河北唐山063000 [2]北京房山良乡医院影像科,北京102401

出　　处：《中华中医药学刊》2019年第3期724-726,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：河北省中医药管理局科研计划项目(2016238)

摘　　要：目的:分析血栓通脉汤联合针刺对脑梗死的疗效及对神经、血管功能的影响。方法:115例急性脑梗死患者,按照随机数字表法分成两组。对照组患者给予西医常规治疗,观察组患者在此基础上给予血栓通脉汤联合针刺治疗。连续治疗12周,对比两组治疗效果、治疗前后神经功能、血管功能及不良反应的差异。结果:治疗后观察组总有效率明显高于对照组,组间有显著的统计学差异(P<0.05)。治疗前两组患者NIHSS评分、GCS评分无统计学差异(P>0.05);治疗后观察组NIHSS评分低于对照组,GCS评分高于对照组,组间有显著的统计学差异(P<0.05)。治疗前两组患者血清ET-1、NO水平无统计学差异(P>0.05);治疗后观察组血清ET-1水平低于对照组,NO水平高于对照组,组间有显著的统计学差异(P<0.05)。治疗期间两组间未见明显的不良反应。结论:血栓通脉汤联合针刺治疗急性脑梗死疗效确切,可较好的改善患者神经功能缺损和血管内皮功能损伤程度。Objective: To analyze the effect of Xueshuan Tongmai Decoction combined with acupuncture on cerebral infarction and its effect on nerve and vascular function. Methods: A total of 115 patients with acute cerebral infarction were selected and divided into two groups according to the random digital table method. The patients in the control group were given conventional treatment with western medicine. Oil this basis, the patients in the observation group were treated with Xueshuan Tongmai Decoction to assist the acupuncture. After 12 weeks of continuous treatment, the effects of treatment, nerve function, vascular function and adverse reaction before and after treatment were compared between the two groups. Results: After treat me nt, the total effective rate of the observation group was sign ificantly higher than that of the control group, and there was significant difference between the groups ( P < 0. 05 ). Before treatment, there was no significant difference in NIHSS score or GCS score between the two groups( P >0. 05 ). After treatment, the NIHSS score of the observation group was lower than that of the control group, and the GCS score was higher than that of the control group. There was a significant difference between the two groups ( P < 0. 05 ). Before treatment, there was no significant difference in serum ET - 1 or NO levels between the two groups( P〉0. 05). After treatment, the serum ET - 1 level in the observation group was lower than that in the control group, and the level of NO was higher than that in the control group. There was a significant difference between the two groups ( P < 0. 05 ). There was no obvious adverse reaction between the two groups during the treatment. Conclusion: Xueshuan Tongmai Decoction combined with acupuncture at Tongli ( HT5 ) is effective in treating acute cerebral infarction, which can better improve neurological impairment and vascular endothelial dysfunction.

关 键 词：血栓通脉汤 针刺 急性脑梗死 神经功能 血管功能 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R245.31[医药卫生—临床医学]