低剂量灌注CT成像诊断胰腺癌的研究进展  

Research and Progress of Low Dose CT Perfusion Imaging on Diagnosis of Pancreatic Cancer

作　　者：刘丰[1] 康洋铭 周阳[1] 姜佳琪 张洪博 张亚楠 纪凤颖[1] LIU Feng;KANG Yang-ming;ZHOU Yang;JIANG Jia-qi;ZHANG Hong-bo;ZHANG Ya-nan;JI Feng-ying(CT department,The First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China;Department of CT Room,The Second People's hospital in Pulandian District,Dalian,Liaoning,116222,China)

机构地区：[1]哈尔滨医科大学附属临床第一医学院CT室,黑龙江哈尔滨150001 [2]大连市普兰店区第二人民医院CT室,辽宁大连116222

出　　处：《现代生物医学进展》2019年第3期593-595,571,共4页Progress in Modern Biomedicine

基　　金：黑龙江省自然科学基金面上项目(D201232)

摘　　要：随着MSCT的不断发展以及检查技术的不断完善,胰腺疾病的诊断率也不断进步。CT可以对胰腺进行普通平扫、多期增强扫描及CT灌注扫描(CTPI)。其中,普通平扫及增强扫描对小的胰腺癌病灶诊断率较低;普通灌注扫描可以通过监测胰腺组织血流动力学评价胰腺功能,对于早期胰腺癌的诊断率较高,但辐射剂量也较高,因此对患者的远期影响较大。因此,在满足对胰腺癌疾病诊断条件的前提下,减少CT扫描对患者的辐射剂量是目前临床研究的热点。灌注扫描通过监测患者血流量(BF)、血容量(BV)对正常胰腺及胰腺癌病灶进行观察,能够在减少辐射剂量的同时获得灌注数据,从而提供更多的诊断信息,进而满足临床诊断的要求。With the continuous development of MSCT and the continuous improvement of the inspection technology, the diagnostic rate of pancreatic disease also increased. CT can be performed with plain, multi phase and CT perfusion scan(CTPI). Among them, the ordinary scan and enhanced scan in the diagnosis of small pancreatic carcinoma rate is low;the common pancreatic tissue perfusion scan can be detected by monitoring the hemodynamic evaluation of pancreatic function, for the early diagnosis of pancreatic cancer was higher, but the radiation dose is higher, so the impact on patients with long-term large. Therefore, in order to meet the conditions for the diagnosis of pancreatic cancer, it is a hot spot of clinical research to reduce the radiation dose of CT scanning to patients. The blood flow perfusion scan patient monitoring(BF), blood volume(BV) of normal pancreas and pancreatic carcinoma were observed, can reduce the radiation dose and perfusion data, so as to provide more diagnostic information, and meet the demands of clinical diagnosis.

关 键 词：胰腺癌 早期诊断 低剂量 CT诊断 

分 类 号：R735.9[医药卫生—肿瘤] R814.42[医药卫生—临床医学]