食管鳞癌三维放射治疗累及野和扩大野疗效比较  

Comparison of the efficacy of involved field and extended field in three-dimensional radiotherapy for esophageal squamous cell carcinoma

作　　者：陈燕芳 刘万珍 阮文红 章耀鸿 魏晓龙[2] Chen Yanfang;Liu Wanzhen;Ruan Wenhong;Zhang Yaohong;Wei Xiaolong(Chaozhou People's Hospital 5210011;Cancer Hospital Affiliated to Shantou University 5150412)

机构地区：[1]潮州市人民医院,521001 [2]汕头大学附属肿瘤医院,515041

出　　处：《中国社区医师》2019年第11期15-16,共2页Chinese Community Doctors

摘　　要：目的:探讨不可手术食管鳞癌三维适形放疗淋巴结引流区累及野照射的疗效。方法:收治行3D-CRT/IMRT放疗的食管鳞癌患者90例。根据CTV的勾画范围不同分为累及野组和扩大野组,比较相关指标。结果:累及野组对比扩大野组的放射性食管炎及放射性肺炎发生率明显减少,其中3、4级放射性肺炎的发生率分别为5%、14.4%,差异有统计学意义(P<0.05)。累及野组比扩大野组的放疗急性反应发生率低且反应较轻,差异有统计学意义(P<0.05)。结论:局部晚期食管鳞状细胞癌患者行累及野放疗是有效且安全的。Objective:To investigate the curative effect of non-operative three-dimensional conformal radiotherapy for esophageal squamous cell carcinoma with lymph node drainage area involving field irradiation.Methods:90 patients with esophageal squamous cell carcinoma treated by 3d-crt /IMRT were selected.According to the different range of CTV,they were divided into the involved field group and the expanded field group,we compared the relevant indicators.Results:The incidence of radiation esophagitis and pneumonia in the involved field group was significantly lower than that in the expanded field group.The incidence rate of grade 3 and grade 4 radioactive pneumonia was 5% and 14.4%,the difference was statistically significant(P<0.05).The incidence of acute radiotherapy response in the involved field group was lower than that in the expanded field group,and the response was lighter,the difference between the two groups was statistically significant(P<0.05).Conclusion:The involved field radiotherapy for patients with local advanced esophageal squamous cell carcinoma was safe and effective.

关 键 词：食管鳞癌放疗 累及野 扩大野 疗效 

分 类 号：R735.1[医药卫生—肿瘤]