脑卒中伴不同程度抑郁患者的临床特点及相关因素分析  

Clinical characteristics and related factor analysis of stroke patients with different degrees of depression

作　　者：王小莉[1] 李鑫铭[1] WANG Xiao-li;LI Xin-ming(Rehabilitation Medicine Department, Xi'an Gaoxin Hospital, Xi'an 710075, China)

机构地区：[1]西安高新医院康复医学科,陕西西安710075

出　　处：《临床医学研究与实践》2019年第12期89-91,共3页Clinical Research and Practice

摘　　要：目的分析脑卒中伴不同程度抑郁患者的临床特点及相关因素。方法回顾性分析就诊于我院神经内科的150例首次脑卒中患者的临床资料,根据HAMD评分将其分为无抑郁组(<7分)和抑郁组(≥7分),比较两组一般资料、神经功能、社会支持度及日常生活活动能力,并分析抑郁发生的相关影响因素。按HAMD评分将抑郁组分为轻度、中度、重度,通过Spearman等级相关分析各抑郁程度的相关因素。结果 150例脑卒中患者中有52例抑郁,其中轻度、中度、重度各35例、11例、6例;抑郁组受教育年限、BI指数、SSRS评分均低于无抑郁组,且女性、高血压、糖尿病、心脏病占比及NIHSS评分均高于无抑郁组(P<0.05);Logistic回归分析发现,性别、高血压、心脏病、NIHSS评分均是脑卒中后抑郁发生的危险因素,BI指数是保护因素(P<0.05);Spearman等级相关分析显示,脑卒中抑郁程度与受教育年限、BI指数、SSRS评分呈负相关(r<0,P<0.05),与女性、糖尿病、高血压、心脏病、NIHSS评分呈正相关(r>0,P<0.05)。结论脑卒中伴抑郁发生率较高,其严重程度可能与患者性别、心脏病及糖尿病等合并症、神经功能及社会支持度等相关,故临床应高度重视并积极控制存在的风险因素。Objective To analyze the clinical characteristics and related factors of stroke patients with different degrees of depression. Methods The clinical data of 150 patients with first stroke admitted in the neurology department of our hospital were retrospectively analyzed. The patients were divided into non-depression group(<7 points) and depression group(≥7 points) according to the HAMD score. The general data, neurological function and social support degree and activity of daily living between the two groups were compared, and the related factors of depression were analyzed.According to the HAMD score, the depression group was divided into mild, moderate and severe depression, and the related factors of depression degree were analyzed by Spearman rank correlation. Results There were 52 cases of depression in 150 cases of stroke, including 35 mild cases, 11 moderate cases and 6 severe cases. Years of education, the scores of BI index and SSRS in the depression group were lower than those in the non-depression group, and the proportion of women,hypertension, diabetes, heart disease and NIHSS score were higher than those in the non-depression group(P<0.05). Logistic regression analysis showed that the gender, hypertension, heart disease, NIHSS score were the risk factors for post-stroke depression, and the BI index was the protective factor(P<0.05). Spearman rank correlation analysis showed that the degree of depression in stroke patients had negative correlation with the education years and scores of BI index and SSRS(r<0, P<0.05),and had positive correlation with the female, diabetes, hypertension, heart disease and NIHSS score(r >0, P <0.05).Conclusion The incidence of stroke with depression is higher, and its severity may be related to the gender, complications such as heart disease and diabetes, neurological function and social support. Therefore, it is necessary to attach great importance and actively control the existing risk factors in the clinic.

关 键 词：脑卒中 抑郁 HAMD 

分 类 号：R743.3[医药卫生—神经病学与精神病学]