中药治疗肠系膜淋巴结炎临床疗效观察  

Clinical efficacy and safety of traditional Chinese medicine in the treatment of mesenteric lymphadenitis

作　　者：张雪丽[1] 董秀兰[1] 李亚红[1] 许华[1] 陈火莲[1] ZHANG Xue-li;DONG Xiu-lan;LI Ya-hong;XU Hua;CHEN Huo-lian(Department of Pediatrics, the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, Guangdong, CHINA)

机构地区：[1]广州中医药大学第一附属医院儿科,广东广州510405

出　　处：《海南医学》2019年第7期896-898,共3页Hainan Medical Journal

摘　　要：目的观察中药治疗肠系膜淋巴结炎的临床疗效和安全性。方法选择2016年4月至2018年7月广州中医药大学第一附属医院儿科诊治的40例肠系膜淋巴结炎患儿为研究对象,根据随机数表法将患儿分为对照组和观察组,每组20例,对照组患儿给予基础抗感染治疗3 d,观察组患儿则在对照组基础上增加中药治疗3 d,方剂由姜厚朴10 g、醋延胡索10 g、佛手10 g、山楂10 g、麦芽10 g、鸡内金10 g、连翘10 g、夏枯草15 g、浙贝母10 g、蒲公英10 g组成,水煎剂,每天1剂,分早晚两次服用。观察并比较两组患儿的临床疗效、退热时间、腹痛消失时间、肠系膜淋巴结缩小程度、外周血白细胞(WBC)计数、超敏C反应蛋白(hs-CRP)水平和并发症的发生情况。结果观察组患儿的治疗总有效率为100.0%,明显高于对照组的80.0%,差异有统计学意义(P<0.05);观察组患儿的退热时间、腹痛消失时间分别为(2.03±0.69) h、(2.83±0.75) h,均小于对照组的(3.69±0.92) h、(4.15±1.08) h,差异均有统计学意义(P<0.05);两组患儿治疗后肠系膜淋巴结大小、外周血WBC、hs-CRP值显著降低,观察组肠系膜淋巴结大小、外周血WBC、hs-CRP值分别为(8.72±1.16) mm、(4.14±1.27)×109/L、(6.03±2.51) mg/L,均明显小于或低于对照组的(10.21±2.05) mm、(5.02±0.93)×109/L、(12.01±4.35) mg/L,差异均有统计学意义(P<0.05);两组患儿治疗过程中均未出现严重并发症。结论在西医治疗基础上增加中药治疗可缓解肠系膜淋巴结炎患儿临床症状,提高治疗效果,且不增加并发症风险,优于单独西药治疗。Objective To observe the clinical efficacy and safety of traditional Chinese medicine in the treatment of mesenteric lymphadenitis. Methods Forty children with mesenteric lymphadenitis treated in Department of Pediatrics, the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine from April 2016 to July2018 were selected as the research objects. According to the random number table method, the children were divided into two groups, with 20 cases in each group. The control group received basic anti-infective treatment for 3 days, and the study group was additionally treated with traditional Chinese medicine for 3 days on the basis of the control group. The prescription consists of Ginger Magnolia Officinalis 10 g, Vinegar Corydalis 10 g, Bergamot 10 g, Hawthorn 10 g, Malt10 g, gallus domesticus brisson 10 g, Forsythia suspense 10 g, Prunella vulgaris 15 g, Fritillaria thunbergii 10 g, Dandelion 10 g, in water decoction, one dose a day, twice a day(in the morning and evening). The curative effect, time of fever abatement, time of abdominal pain disappearance, mesenteric lymph node shrinkage, peripheral blood leukocyte(WBC)count, high sensitivity C-reactive protein(hs-CRP) level, and complication rate of the two groups were observed and compared. Results The effective rate of treatment(100.0%) in the observation group was higher than that of control group(80.0%), and the difference was statistically significant(P<0.05). The time of fever abatement and abdominal pain disappearance in study group were(2.03 ± 0.69) h and(2.83 ± 0.75) h, respectively, which were significantly less than(3.69±0.92) h and(4.15±1.08) h in the control group(P<0.05). After treatment, the size of mesenteric lymph nodes, levels of WBC, and hs-CRP in peripheral blood were significantly decreased in the two groups. The size of mesenteric lymph nodes, WBC, and hs-CRP in peripheral blood of the study group were(8.72±1.16) mm,(4.14±1.27)×10^9/L,(6.03±2.51) mg/L after treatment, respectively, which were significantl

关 键 词：中药 肠系膜淋巴结炎 腹痛 淋巴结 疗效 

分 类 号：R574[医药卫生—消化系统]