上海某三甲医院结直肠癌相对无症状人群结肠镜检查中息肉与癌检出率现状及影响因素分析  

Prevalence and influencing factors for polyp and cancer detection rate in colonoscopy in relatively asymptomatic population of colorectal cancer in a single tertiary hospital in Shanghai

作　　者：王成龙 王颢 赵子夜 邢俊杰[1] 于恩达 Wang Chenglong;Wang Hao;Zhao Ziye;Xing JunJie;Yu Enda(Department of Colorectal Surgery,Changhai Hospital Affiliated to Naval Military Medical University,Shanghai 200433,China;Department of Gastrointestinal Endoscopy Center,Changhai Hospital Affiliated to Naval Military Medical University,Shanghai 200433,China;Department of Surgery,No. 951 Hospital of Chinese People’s Liberation Army,Korla 841007,Xinjiang Uygur Autonomous Region,China)

机构地区：[1]海军军医大学附属长海医院肛肠外科,上海200433 [2]中国人民解放军第951医院外一科,新疆库尔勒841007 [3]海军军医大学附属长海医院消化内镜中心,上海200433

出　　处：《结直肠肛门外科》2019年第2期131-136,共6页Journal of Colorectal & Anal Surgery

基　　金：973计划课题(2015CB554001);国家重点研发计划(2017YFC1308800);上海市科委科研计划项目(13JC1407200);第二军医大学精准医学转化应用研究专项(2017JZ19);长海医院"1255"学科建设计划(CH125530800)

摘　　要：目的分析结直肠癌相对无症状人群结肠镜检查中息肉与癌检出率和分布情况,并探讨其影响因素。方法回顾性分析2015年上海长海医院消化内镜中心接受结肠镜检查的17 205例相对无症状受检者资料,按照不同性别、年龄层次、肠道准备质量进行分组,统计分析各组息肉与癌检出率。结果 17 205例相对无症状受检者总体息肉检出率为30.58%;男性为36.17%,女性为24.08%,两者间差异有统计学意义(P <0.05)。总体息肉检出率随着年龄的增长而增高,男性与女性均如此(P <0.05),各年龄组男性息肉检出率均高于女性(均P <0.05),肠道准备质量优良组息肉检出率高于欠佳组(P <0.05)。总体癌检出率为2.62%;男性为2.80%,女性为2.41%,两者间差异无统计学意义(P <0.05)。总体癌检出率随着年龄的增长而升高(P <0.05),50～59岁、60～69岁年龄组男性癌检出率均高于女性(均P <0.05),肠道准备质量优良组癌检出率高于欠佳组(P <0.05)。结论在结直肠癌相对无症状人群中息肉和癌检出率均随年龄的增长而升高,且男性息肉检出率高于女性,良好的肠道准备有助于提升息肉和癌的检出率,但不同性别肠癌发生风险高低的差异仍需要更深入的研究进一步证实。临床中应关注相对无症状人群这一概念。Objectives To investigate prevalence and distribution of polyp and cancer detection rate in colonoscopy in a relatively asymptomatic of colorectal cancer population and their influencing factors.Methods This was a retrospective analysis of clinical data of 17,205 relatively asymptomatic population of colorectal cancer who received colonoscopy in Gastrointestinal Endoscopy Center in Changhai Hospital,Shanghai,in 2015.Participants were grouped by sex,age groups,and quality of bowel preparation and analyzed,by groups,polyp detection rate and cancer detection rate.Results Overall polyp detection rate was 30.58%in 17,205 participants,36.17%in men and 24.08%in women,with significant between-sex difference(P<0.05).Polyp detection rate increased significantly with age in both gender(P<0.05),was significantly higher in men than in women in all age groups(P<0.05),and was significantly higher in those with better than those with poorer bowel preparation(P<0.05).Overall cancer detection rate was 2.62%,2.80%in men and 2.41%in women,with no significant between-sex difference(P>0.05).Cancer detection rate increased significantly with age(P<0.05),was significantly higher in men than in women in age groups of 50~59 and 60~69 years old(P<0.05),and was significantly higher in those with better than in those with poorer bowel preparation(P<0.05).Conclusion Polyp detection rate and cancer detection rate increase with age in relative asymptomatic of colorectal cancer population.Prevalence of polyps under colonoscopy was higher in men than in women.Better bowel preparation improves polyps and cancer detection rate.Further studies are required to investigate sex-related differences in risk of colorectal cancer.The concept of relatively asymptomatic population should be paid attention to in clinical.

关 键 词：结直肠癌 相对无症状人群 结肠镜检查 息肉检出率 癌检出率 肠道准备 

分 类 号：R735.3[医药卫生—肿瘤]