干眼病的病因、发病机制及治疗进展  

SUN Ziwen^1, CUI Hongwei^2, SUN XilingEtiology, pathogenesis, and management of dry eye

作　　者：孙子雯 崔洪玮 孙喜灵[3] 陈晨[1] 张璐[1] 胡竹林[1] SUN Ziwen;CUI Hongwei;SUN Xiling;CHEN Chen;ZHANG Lu;HU Zhulin(Department of Ophthalmology, The Fourth Affiliated Hospital of Kunming Medical University/The Sceond People's Hospital of Yunnan Province/Yunnan Province Institute of Ophthalmology/Yunnan Key Laboratory of Ocular Disease Prevention and Control, Kunming 650021, Yunnan, China;Department of Neurosurgery, Clinical Medicine College, Wei fang Medical University, Weifang 261036, Shandong, China;Traditional Chinese Medicine, Binzhou Medical University, Integrated Chinese and Western Medicine College, Yantai 264000, Shandong, China)

机构地区：[1]昆明医科大学第四附属医院眼科云南省第二人民医院眼科云南省眼科研究所云南省眼科疾病防治研究重点实验室,云南昆明650021 [2]潍坊医学院临床医学院神经外科,山东潍坊261036 [3]滨州医学院中西医结合学院,山东烟台264000

出　　处：《山东大学耳鼻喉眼学报》2019年第2期159-166,共8页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：院士和领军人才培养(2017HC010);院士专家工作站(2017IC064);云南省卫生科技计划项目(2016NS182)

摘　　要：由于内在因素(泪膜破坏、性激素失调等)和外在因素(环境、手术和药物等)多重因素影响,干眼病患者急剧增多且呈年轻化发展趋势,干眼病目前已成为最常见的眼部疾病之一。回顾近几年的国内外相关文献,就干眼病的主要病因、发病机制及未来治疗突破的方向进行综述。Due to multiple influences of internal factors (tear film destruction, sex hormone disorders) and external factors (environment,surgery, and drugs), patients with dry eye disease have been encountered much more frequently and are presenting at a younger age. Dry eye disease has become one of the most common diseases of the ocular surface, with a multifactorial etiology. This paper reviews the newer reports on etiology, pathogenesis, and management of dry eye.

关 键 词：干眼病 病因学 发病机制 治疗突破方向 

分 类 号：R77[医药卫生—眼科]