功能性氨基酸调控猪氧化应激的研究进展  

Regulation of functional amino acids on oxidative stress in pigs

作　　者：尹杰[1,2] 韩慧 刘泽民 何兴国 李铁军 印遇龙[1] YIN Jie;HAN Hui;LIU ZeMin;HE XingGuo;LI TieJun;YIN YuLong(Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China;University of Chinese Academy of Sciences, Beijing 100049, China;Changsha Green Leaf Biotechnology Co., Ltd., Changsha 410125, Hunan)

机构地区：[1]动物营养生理与代谢过程湖南省重点实验室亚热带农业生态过程重点实验室中国科学院亚热带农业生态研究所,长沙410125 [2]中国科学院大学,北京100049 [3]长沙绿叶生物科技有限公司,长沙410125

出　　处：《中国科学：生命科学》2019年第3期193-201,共9页Scientia Sinica(Vitae)

基　　金：国家自然科学基金(批准号:31272463);国家自然科学基金重大国际合作研究项目(批准号:31110103909)资助;国家重点基础研究发展计划(批准号:2012CB124704)

摘　　要：氧化应激是指人和动物机体自由基产生急剧增多或清除自由基能力下降,从而打破了抗氧化-氧化平衡.在猪生产上,多种因素均能诱导产生氧化应激,其中包括出生应激、断奶应激、饲料霉菌毒素污染以及饲养环境和社会因素等.猪氧化应激发生往往伴随着其他病理因素,对猪生产性能和健康生长具有重要影响.目前,多种功能性氨基酸被报道具有抗氧化能力,包括含硫氨基酸、谷氨酸、精氨酸以及色氨酸等.因此,通过营养干预方法在饲料中补充或添加功能性氨基酸对猪氧化应激具有缓解效应.本文主要就猪出生、断奶、霉菌毒素以及饲养环境造成的氧化应激以及功能性氨基酸营养调控进行了探讨,以期为猪营养研究及功能性氨基酸科学应用提供参考.Rapid generation of free radical species in the body impairs the antioxidant-oxidative balance, which further causes oxidative stress in humans and animals. In the pig industry, various factors can induce oxidative stress, including birth process, weaning stress,mycotoxin contamination, and feeding environment. Oxidative stress is generally accompanied by other pathologies, which further exerts an important effect on growth performance and healthy status. Currently, various functional amino acids(i.e., sulfur-containing amino acids, glutamic acid, arginine, and tryptophan) are reported to exhibit a potential antioxidant ability. Thus, dietary supplementation with functional amino acids may exert a preventive or therapeutic effect on oxidative stress in pigs. This review mainly discusses the birth-, weaning-, mycotoxins-, and feeding environment-induced oxidative stress and nutritional regulation in pigs, which may provide a reference for the study and scientific application in pig nutrition.

关 键 词：猪 氧化应激 氨基酸 营养调控 

分 类 号：S828[农业科学—畜牧学]