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作 者:张云魁[1] 张荣生[1] 张羽捷[1] Zhang Yunkui;Zhang Rongsheng;Zhang Yujie(Department of Thoracic Surgery 3, Shanxi Provincial Cancer Hospital, Taiyuan 030013, China)
出 处:《肿瘤研究与临床》2019年第3期209-213,共5页Cancer Research and Clinic
摘 要:目前手术仍是可切除非小细胞肺癌(NSCLC)的最佳治疗方法。TNM分期是判断手术预后的主要指标,但相同分期患者的预后有很大差异。相关研究显示,NSCLC手术治疗预后影响因素包括肺功能差、患心血管疾病、男性、高龄、有合并疾病、TNM分期较晚、非腺癌、全肺切除等。许多预后因素的研究结果尚存在争议,分子生物学因素、新辅助治疗及辅助治疗对预后的影响还需进一步深入研究。At present, surgery is still the best way to treat resectable non-small cell lung cancer (NSCLC). For clinicians, TNM stage is the main indicator to judge surgical outcomes, but the prognosis of patients with same stages still has big differences. The related studies have shown that the prognostic factors for patients with NSCLC after surgical treatment include poor lung function, the suffering from cardiovascular diseases, male, advanced age, comorbidities, advanced TNM stage, non-adenocarcinoma and pneumonectomy. Many results of prognostic factors research are controversial;meanwhile, the effects of molecular biological factors, neoadjuvant therapy and adjuvant therapy on prognosis still need further study.
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