青少年视网膜色素变性患者光学相干断层扫描图像与眼底荧光血管造影特征分析  

Characteristics analysis of optical coherence tomography and fundus fluorescence angiography image in teenagers primary retinitis pigmentosa

作　　者：徐甄 李雅琢 张议文 陈婷[1] 刘平[1] 张丽娟[1] Xu Zhen;Li Ya-zhuo;Zhang Yi-iven(The Third Ward of ophthalmology, First Affiliated Hospital of Harbin Medical University, Harbin 150001, China)

机构地区：[1]哈尔滨医科大学附属第一医院眼科三病房,150001

出　　处：《中国斜视与小儿眼科杂志》2019年第1期23-24,25,I0002,共4页Chinese Journal of Strabismus & Pediatric Ophthalmology

基　　金：国家自然科学基金面上项目(项目编号81470618)

摘　　要：目的探讨光学相干断层扫描(OCT)联合眼底荧光血管造影(FFA)在青少年原发性视网膜色素变性(RP)患者检查中的影像特征。方法回顾性分析2018年6月至2018年10月RP患者7例(14眼)临床资料,进行OCT及FFA检查,对比分析其影像特征。结果 OCT图像显示视网膜神经上皮外核层变薄,视网膜椭圆体区部分断裂或脱失。FFA图像显示后极部普遍色素上皮脱色素,透见脉络膜背景荧光,色素堆积处遮蔽荧光,屏障失代偿处荧光渗漏。结论 OCT与FFA在RP诊断中各具优势,两者联合应用可为RP的发病机制提供研究资料,极大地提高了影像学检查的诊断价值。Objective To explore the image features of optical coherent tomography ( OCT) joint with fundus fluorescence angiography ( FFA) in teenagers primary retinitis pigmentosa ( RP). Method The clinical data of 7 cases ( 14 eyes) RP patients diagnosed RP between June and October in 2018 were analyzed retrospectively observed, OCT and FFA imaging features were compared and analysed. Results OCT image showed that outer nuclear layer of retinal neuroepithelial become thiner, retina ellipsoid area fractured or depigmentationed. FFA images showed that color in retina pigment epithelium layer dissapeared, background fluorescence of choroids layer could be seen, color accumulation place in retina covered the background fluorescence, fluorescent leakaged in barrier decompensation place. Conclusion OCT and FFA both has its advantages in diagnosis of RP, applications can provide research material for the pathogenesis of RP disease, which greatly improved the diagnostic value of imaging examination.

关 键 词：光学相干断层扫描 眼底荧光血管造影 视网膜色素变性 诊断 

分 类 号：R774.1[医药卫生—眼科]