生物力学因素在青光眼评估中的应用研究综述  

Review of studies on the application of biomechanical factors in the evaluation of glaucoma

作　　者：宋红芳 李琦[1,2] 王宁利 王文佳[1,2] 龙晓雪 刘志成 SONG Hongfang;LI Qi;WANG Ningli;WANG Wenjia;LONG Xiaoxue;LIU Zhicheng(Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application,Beijing 100069,P.R.China;School of Biomedical Engineering,Capital Medical University,Beijing 100069,P.R.China;Beijing Tongren Hospital,Capital Medical University,Beijing 100005,P.R.China)

机构地区：[1]临床生物力学应用基础研究北京市重点实验室,北京100069 [2]首都医科大学生物医学工程学院,北京100069 [3]首都医科大学附属北京同仁医院,北京100050

出　　处：《生物医学工程学杂志》2019年第2期315-319,共5页Journal of Biomedical Engineering

基　　金：北京市自然科学基金(7152022);国家自然科学基金(10802053)

摘　　要：青光眼的生物力学风险因素众多,相互关系纷繁复杂。本文综述了青光眼有关力学作用方面的最新研究状况。在青光眼生物力学研究的发展前景方面,提出了一个全新的生物力学评估指标——压力储备分数(FPR),并提出利用人工智能和机器学习等新技术构建面向临床应用的青光眼风险评估算法和应用系统。There are so many biomechanical risk factors related with glaucoma and their relationship is much complex.This paper reviewed the state-of-the-art research works on glaucoma related mechanical effects.With regards to the development perspectives of studies on glaucoma biomechanics,a completely novel biomechanical evaluation factor--Fractional Flow Reserve(FPR)for glaucoma was proposed,and developing clinical application oriented glaucoma risk assessment algorithm and application system by using the new techniques such as artificial intelligence and machine learning were suggested.

关 键 词：青光眼 眼生物力学 统计分析 研究进展 

分 类 号：R775[医药卫生—眼科]