Correlation between carbohydrate antigen 199 and glycemic control in patients with type 2 diabetes mellitus  

作　　者：Su-Qing Bao Feng-Bo Li Xia Jiang 

机构地区：[1]Department of Endocrinology,Tianjin First Center Hospital,Tianjin 300192,China [2]Department of Orthopedics,Tianjin Hospital,Tianjin 300211,China

出　　处：《Chinese Medical Journal》2019年第8期984-986,共3页中华医学杂志（英文版）

摘　　要：To the Editor:Type 2 diabetes mellitus(T2DM)is a common complex metabolic disorder.Previous studies have reported that T2DM patients posed a risk for pancreatic carcinogenesis.[1]Carbohydrate antigen 199(CA 199)is the biological link among the diseases,and patients with chronic pancreatitis possibly have higher levels of CA 199 than healthy individuals,and chronic pancreatitis has been confirmed to be a risk factor of diabetes mellitus.[2] Thus it is also a symbol for pancreatic tissue damaged that possibly caused by diabetes.So far several mechanisms for the relationship have been proposed,such as increscent inflammation,abnormal metabolic state,insulin resistance,endoplasmic reticulum stress,misadjustment of autophagy,and so on.[1]Haemoglobin Alc(HbAlc)is the most important laboratory parameter indicating glycemic control in T2DM patients.The general target of HbAlc is≤7%for good glycemic control,while HbAlc values over 7%show poor glycemic control.

关 键 词：glycemic control Type 2 DIABETES mellitus(T2DM) PANCREATIC CARCINOGENESIS 

分 类 号：R[医药卫生]