Protective effect of supplementation with Lycium ruthenicum Murray extract from exhaustive exercise-induced cardiac injury in rats  

作　　者：Chien-Wei Hou I-Chen Chen Fang-Rui Shu Chin-Hsing Feng Chang-Tsen Hung 

机构地区：[1]Department of Biotechnology and Pharmaceutical Technology,Yuanpei University of Medical Technology,Hsinchu,Taiwan 30015,China [2]Division of Plastic and Reconstructive Surgery,Department of Surgery,Taichung Veterans General Hospital,Taichung,Taiwan 40705,China [3]Department of Health and Leisure Management,Yuanpei University of Medical Technology,Hsinchu,Taiwan 30015,China

出　　处：《Chinese Medical Journal》2019年第8期1005-1006,共2页中华医学杂志（英文版）

摘　　要：To the Editor:Lycium ruthenicum(L.ruthenicum)Murray contains abundant anthocyanins.The purpose of the present research was to investigate the protective effect of L.ruthenicum extract supplementation on the damage from exhaustive exercise in rats which were treated for seven days before the exhaustive exercise.Exhaustive exercise induced an increase of Serum nitrate(NO)and reactive oxygen species(ROS)levels,but supplementation of L.ruthenicum extract reduced them significantly(P<0.05).Interleukin(IL)-1 and IL-6 were also significantly reduced by L.ruthenicum as compared to the control(P<0.05).Supplementation with L.ruthenicum extract also decreased the creatine kinase isoenzyme MB(CK-MB)generation significantly and ameliorated the myocardial histopathology.

关 键 词：Serum nitrate(NO) reactive oxygen species(ROS) CREATINE kinase ISOENZYME MB(CK-MB) 

分 类 号：R[医药卫生]