Diffusive-stochastic-viscoelastic model on specific adhesion of viscoelastic solids via molecular bonds  

作　　者：Kuncheng He Long Li Jizeng Wang 

机构地区：[1]Key Laboratory of Mechanics on Disaster and Environment in Western China, Ministry of Education, College of Civil Engineering and Mechanics, Lanzhou University, Lanzhou 730000, China

出　　处：《Acta Mechanica Sinica》2019年第2期343-354,共12页力学学报（英文版）

基　　金：the National Natural Science Foundation of China (Grants 11472119 and 11602099);the Fundamental Research Funds for the Central Universities (Grant lzujbky-2017-ot11);the 111 Project (Grant B14044).

摘　　要：A diffusive-stochastic-viscoelastic model is proposed for the specific adhesion of viscoelastic solids via stochastically formed molecular bonds. In this model, we assumed that molecular level behaviours, including the diffusion of mobile adhesion molecules and stochastic reaction between adhesion molecules and binding sites, obey the Markovian stochastic processes, while mesoscopic deformations of the viscoelastic media are governed by continuum mechanics. Through Monte Carlo simulations of this model, we systematically investigated how the competition between time scales of molecular diffusion, reaction, and deformation creep of the solids may influence the lifetime and dynamic strength of the adhesion. We revealed that there exists an optimal characteristic time of molecule diffusion corresponding to the longest lifetime and largest adhesion strength, which is in good agreement with experimental observed characteristic time scales of molecular diffusion in cell membranes. In addition, we identified that the media viscosity can significantly increase the lifetime and dynamic strength, since the deformation creep and stress relaxation can effectively reduce the concentration of interfacial stress and increases the rebinding probability of molecular bonds.

关 键 词：SPECIFIC ADHESION MOLECULAR BONDS Diffusion Monte Carlo simulation CONTINUUM mechanics 

分 类 号：O3[理学—力学]