水通道蛋白8在肝病治疗中的潜在价值  

Potential value of aquaporin-8 in treatment of liver diseases

作　　者：彭欣 卿笃信[1] PENG Xin;QING Duxin(Department of Gastroenterology,The Second Xiangya Hospital of Central South University,Changsha 410011,China)

机构地区：[1]中南大学湘雅二医院消化内科,长沙410011

出　　处：《临床肝胆病杂志》2019年第5期1140-1142,共3页Journal of Clinical Hepatology

基　　金：湖南省自然科学基金面上项目(2017JJ2361)

摘　　要：水通道蛋白参与胆汁代谢、细胞信号转导等过程。简述了水通道蛋白在胆汁淤积性肝病、酒精性肝病、肝性脑病、肝癌中的作用及机制,提出了水通道蛋白激动剂可能是未来肝病治疗的方向,为肝病治疗提供了新思路。Aquaporins are involved in bile metabolism and cell signal transduction. This article briefly describes the role and mechanism of action of aquaporins in cholestatic liver disease,alcoholic liver disease,hepatic encephalopathy,and liver cancer and points out that aquaporin agonists may be a future direction of treatment of these liver diseases,which provides new ideas for the treatment of liver diseases.

关 键 词：肝疾病 水孔蛋白质类 治疗学 综述 

分 类 号：R575[医药卫生—消化系统]