以血管为轴心的巨块型肝癌三维可视化评估及虚拟现实技术研究  

Three-dimensional visualization evaluation and VR study of giant liver cancer with blood vessels as the axis

作　　者：曾思略 祝文[1] 方驰华[1] 何松盛 张鹏[1] 文赛 张可 Zeng Silue;Zhu Wen;Fang Chihua;He Songsheng;Zhang Peng;Wen Sai;Zhang Ke(The First Department of Hepatobiliary Surgery,Zhujiang Hospital,Southern Medical University,Guangzhou510282 ,China;Chengdu Co-innovation Co. ,Ltd 610000,China)

机构地区：[1]南方医科大学珠江医院肝胆一科,广州510282 [2]成都中创五联科技有限公司,610000

出　　处：《中华普通外科杂志》2019年第4期323-327,共5页Chinese Journal of General Surgery

基　　金：“十三五”国家重点研发计划数字诊疗装备研发重点专项(2016YFC0106500);国家自然科学基金重大科研仪器研制项目(81627805);NSFC-广东联合基金项目(U1401254);广东省科技计划项目(2017ZC0110);广州市科技计划项目(201604020144).

摘　　要：目的 研究以血管为轴心三维可视化分型及虚拟现实技术在巨块型肝癌的临床应用价值.方法 经病史、影像和化验检查,诊断为原发性巨块型肝癌的13例患者,采集薄层CT数据,进行三维重建并转化为VR模型,分析肿瘤与周围重要结构的解剖关系,进行以血管为轴心的术前评估分型及手术规划,指导术中导航,结合术中快速病理检查进行一致性验证.结果 13例患者均成功实现三维重建及VR模型转化.13例患者根据以血管为轴心三维可视化分型分别为:Ⅰa型1级3例;Ⅰa型2级2例;Ⅱa型2级1例;Ⅱb型3级1例;Ⅱc型3级2例;Ⅱa型3级4例.结论 三维可视化及VR技术能够提供肝癌病灶和脉管解剖结构的综合信息,在巨块型肝癌手术应用中有重要的价值.Objective To explore the clinical application value of three-dimensional visualization of blood vessels as the axis and virtual reality technology in giant liver cancer.Methods Thin-layer CT image data of 13 patients who were diagnosed as giant primary liver cancer were collected for three-dimensional reconstruction,and then transformed into VR model.The anatomical relationship between the tumor and its surrounding important structures was analyzed.The preoperative evaluation,classification and surgical planning based on blood vessels as the axis were carried out to guide intraoperative navigation.The consistency was verified by the intraoperative rapid pathological examination.Results 13 patients successfully achieved 3D reconstruction and VR model transformation.According to the 3D visualization classification of blood vessels as the axis.There were three cases of type Ⅰ a grade 1,two cases of type Ⅰa grade 2;one case of type Ⅱ a grade 2;one case of type Ⅱ b grade 3;two cases of type Ⅱ c grade 3;four cases of type Ⅱ a grade 3.Conclusions Three-dimensional visualization and VR technology can provide comprehensive information on the anatomical structure of liver cancer lesions and blood vessels,which is of great value in the application of giant liver cancer surgery.

关 键 词：肝肿瘤 成像 三维 

分 类 号：R735.7[医药卫生—肿瘤]