速激肽及其受体与抑郁症的研究进展  

Research progress on the relationship between tachykinin/ tachykinin receptors and depression

作　　者：相丹 王高华[1] 刘忠纯[1] Xiang Dan;Wang Gaohua;Liu Zhongchun(Department of Psychiatry,Renmin Hospital of Wuhan University,Wuhan 430061,China)

机构地区：[1]武汉大学人民医院精神卫生中心,430061

出　　处：《神经疾病与精神卫生》2019年第3期304-308,共5页Journal of Neuroscience and Mental Health

基　　金：国家重点研发计划(2018YFC1314600);国家自然科学基金(81771472).

摘　　要：速激肽及其受体广泛分布于大脑中枢神经系统中,特别是与情绪相关的边缘系统中。已有大量研究证据表明速激肽及其受体与抑郁症的发病密切相关。现对速激肽及其受体与抑郁症关系的研究进展进行综述,为明确抑郁症的发病机制及治疗靶点提供新方向。The tachykinin/ tachykinin receptors are widely distributed in the central nervous system of the brain,especially in the limbic system associated with emotion.Accumulating evidence has indicated that the tachykinin/ tachykinin receptors may contribute to the pathophysiology of depression.This article reviews the research on the relationship between tachykinin/ tachykinin receptors and depression,and it may enrich the understanding of the pathological processes of depression and provide insights into therapeutic approaches for its treatment.

关 键 词：抑郁症 速激肽类 受体 速激肽 综述 

分 类 号：R749.4[医药卫生—神经病学与精神病学]