牙科树脂系统抗菌及生物活性的研究进展  

Research progress of antibacterial and biological activity of dental resin systems

作　　者：刘璐 洪丽华[1] 张志民[1] 杨瑶瑶[1] 曲添[1] LIU Lu;HONG Lihua;ZHANG Zhimin;YANG Yaoyao;QU Tian(Department of Oral Endodontics),Hospital of Stomatology,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学口腔医院牙体牙髓病科,吉林长春130021 [2]吉林大学口腔医学院生物医学工程实验室,吉林长春130021

出　　处：《口腔医学》2019年第4期356-359,共4页Stomatology

基　　金：国家自然科学基金项目(81170945)

摘　　要：牙菌斑是一种复杂的生物膜,参与龋病的发展过程,生物膜于牙齿组织和修复材料上的堆积,是继发龋发生最重要的因素之一。具有抗菌功效的复合树脂材料主要利用抗菌单体、抗菌填料、抗菌与再矿化联合、生物活性树脂、表面活性剂等,通过杀菌、抑菌、抑制蛋白吸附、调节生物膜菌群多种方式来减少牙齿组织与牙科材料表面的菌斑堆积,防止继发龋的发生。本文以抗菌及生物活性牙科树脂组成为分类描述了迄今为止所研究材料的进展和局限性,同时阐述其抗菌作用机制。Plaque is a complex biofilm that participates in the development of caries.The accumulation of biofilm on dental tissues and materials is one of the most important factors in the development of secondary caries.The composite resin material with antibacterial effect mainly utilizes antibacterial monomer,antibacterial filler,antibacterial and remineralization combination,bioactive resin,surfactant,etc..It can reduce plaque accumulation on the surface of dental tissues and dental materials by sterilization,bacteriostasis,inhibiting protein adsorption,and regulating biofilm to prevent secondary caries.This article describes the progress and limitations of the materials studied so far in terms of the composition of antibacterial and bioactive dental resins,and at the same time describes its antibacterial mechanism.

关 键 词：抗菌性 树脂基牙科材料 作用机制 生物活性 

分 类 号：R781[医药卫生—口腔医学]