2148例淋巴瘤临床病理分析  

Clinicopathological Analysis of 2148 Cases of Lymphoma

作　　者：权小英 张智慧[2] Quan Xiaoying;Zhang Zhihui(The Sixth People's Hospital of Chengdu,Chengdu,Sichuan 610041;Sichuan Cancer Hospital,Chengdu,Sichuan 610041,China)

机构地区：[1]成都市第六人民医院,四川成都610051 [2]四川省肿瘤医院,四川成都610041

出　　处：《四川医学》2019年第4期334-339,共6页Sichuan Medical Journal

基　　金：四川省卫生厅科学研究项目(编号:090528)

摘　　要：目的根据2008版WHO造血淋巴组织肿瘤分类标准,探讨淋巴瘤的临床病理学特征。方法回顾性分析四川省肿瘤医院诊治的2148例淋巴瘤,分析其临床病理学特征。结果①非霍奇金淋巴瘤2085例(97. 07%),霍奇金淋巴瘤63例(2. 93%)。其中B细胞淋巴瘤1600例(76. 74%),T/NK细胞淋巴瘤485例(23. 26%)。非霍奇金淋巴瘤中前五位分别是弥漫大B细胞淋巴瘤1171例(56. 16%),结外NK/T细胞淋巴瘤(鼻型) 295例(14. 15%),滤泡淋巴瘤103例(4. 94%),套细胞淋巴瘤97例(4. 65%),结外黏膜相关淋巴组织淋巴瘤83例(3. 98%)。霍奇金淋巴瘤以结节硬化型最常见33例(52. 38%)。②弥漫大B细胞淋巴瘤最常见结外部位为扁桃体169例(14. 43%),结外NK/T细胞淋巴瘤最常见结外部位为鼻腔255例(86. 44%)。结论弥漫大B细胞淋巴瘤是非霍奇金淋巴瘤最常见亚型,结节硬化型是霍奇金淋巴瘤最常见亚型。扁桃体是弥漫大B细胞淋巴瘤最常见结外部位,鼻腔是结外NK/T细胞淋巴瘤最常见结外部位。Objective To investigate the clinicopathological characteristics of lymphoma according to the 2008 WHO classification criteria for hematopoietic lymphoid tissue tumors.Methods We retrospectively analyzed 2148 cases of lymphoma that were diagnosed and treated in Sichuan Cancer Hospital and analyzed their clinicopathological features.Results ①2085 cases of non-Hodgkin's lymphoma(97.07%)and 63 cases of Hodgkin's lymphoma(2.93%).Among them,1600 cases were B-cell lymphoma(76.74%)and 485 cases were T/NK cell lymphoma(23.26%).The top five non-Hodgkin's lymphomas were diffuse large B lymphoma in 1171 cases(56.16%),extranodal NK/T lymphoma(nasal type)in 295 cases(14.15%),follicular lymphoma in 103 cases(4.94%),mantle cell lymphoma in 97 cases(4.65%)and extranodal mucosa-associated lymphoid tissue lymphoma in 83 cases(3.98%).Thirty-three cases(52.38%)of Hodgkin's lymphoma were nodular sclerosis.②The most common extranodal location of diffuse large B-cell lymphoma was tonsil in 169 cases(14.43%)and nasal cavity in 255 cases(86.44%)of extranodal NK/T-cell lymphoma.Conclusion Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin's lymphoma,and nodular sclerosis is the most common subtype of Hodgkin's lymphoma.Tonsil is the most common extranodal site in diffuse large B-cell lymphoma,and nasal cavity is the most common extranodal site in extranodal NK/T-cell lymphoma.

关 键 词：淋巴瘤 临床特征 病理 

分 类 号：R733.4[医药卫生—肿瘤]