MRI联合CT诊断鼻咽癌患者早期颅底骨侵犯的价值及其对临床决策的影响  

Value of MRI combined with CT in the diagnosis of early skull base invasion in patients with nasopharyngeal carcinoma and its influence on clinical decision-making

作　　者：凌鑫 张培栋 汪娟 LING Xin;ZHANG Peidong;WANG Juan(Department of Radiology, Changhai Hospital, Affiliatedto Naval Military Medical University, Shanghai, 200433,China;Department of Emergency, Shanghai EasternHospital, Shanghai, 200438, China)

机构地区：[1]海军军医大学附属长海医院影像医学科,上海200433 [2]上海市东医院急诊科,上海200438

出　　处：《中国耳鼻咽喉头颈外科》2019年第4期187-190,共4页Chinese Archives of Otolaryngology-Head and Neck Surgery

摘　　要：目的探讨MRI联合CT诊断鼻咽癌患者早期颅底骨侵犯的价值及其对临床决策的影响。方法随机选取我院在2016年4月～2018年4月就诊的200例鼻咽癌患者为研究对象,按数字表法将其分为对照组和研究组,对照组给予MRI诊断,研究组给予MRI联合CT诊断,研究两组患者的诊断结果、满意度、诊断效能、检出情况。结果研究组的诊断结果显著好于对照组(P<0.05);研究组的满意程度显著高于对照组(P<0.05);研究组的敏感度、ROC下面积、假阳性率显著高于对照组(P<0.05),研究组的特异度、假阴性率以及错诊率显著小于对照组(P<0.05);研究组的检出率显著高于对照组(P<0.05)。结论 MRI联合CT诊断鼻咽癌患者早期颅底骨侵犯具有突出的临床价值,值得在临床上进一步推广应用。OBJECTIVE To investigate the value of MRI combined with CT in the diagnosis of early skull base invasion in nasopharyngeal carcinoma(NPC) patients and its influence on clinical decision-making. METHODS A total of 200 patients with nasopharyngeal carcinoma were randomly selected from April 2016 to April 2018 in our hospital. They were divided into control group and research group according to digital table method. The control group was given MRI diagnosis,and the research group was given MRI combined with CT diagnosis. The diagnosis results,satisfaction,diagnostic efficiency and detection rates of the two groups were studied. RESULTS The diagnostic results of the study group were significantly better than those of the control group(P <0.05);The satisfaction degree of the study group was significantly higher than that of the control group(P <0.05);The sensitivity,area under ROC and false positive rate of the study group were significantly higher than those of the control group(P <0.05);The specificity,false negative rate and misdiagnosis rate of the study group were significantly lower than those of the control group(P <0.05);The detection rate of the study group was significantly higher than that of the control group(P<0.05). CONCLUSION MRI combined with CT in the diagnosis of nasopharyngeal carcinoma patients with early skull base invasion has prominent clinical value,which is worthy of further clinical application.

关 键 词：鼻咽肿瘤 诊断 MRI CT 早期颅底骨侵犯 临床决策 

分 类 号：R739.63[医药卫生—肿瘤]