原发性肝脏神经内分泌肿瘤的影像学表现  

Imaging appearance of primary hepatic neuroendocrine carcinomas

作　　者：冯秋霞 刘娜娜 张海龙[1] 徐迅[1] 孙书文 刘希胜[1] FENG Qiuxia;LIU Nana;ZHANG Hailong;XU Xun;SUN Shuwen;LIU Xisheng(Department of Radiology,The First Affiliated Hanjing Medical University,Nanjing 210029,P.R.China)

机构地区：[1]南京医科大学第一附属医院放射科,江苏南京210029

出　　处：《医学影像学杂志》2019年第4期598-602,共5页Journal of Medical Imaging

摘　　要：目的探讨原发性肝脏神经内分泌肿瘤的CT和MRI表现及其特征。方法回顾性分析经病理证实的8例原发性肝脏神经内分泌肿瘤患者的临床、病理及影像学资料。结果本组8例患者中,2例行MR检查,5例行CT平扫及增强检查,1例行CT平扫检查。单发病灶者4例,多发病灶者4例。肿瘤CT平扫均表现为肝内边界清楚的低密度肿块,病灶中央可见不规则形坏死区,3例病灶周围多发子灶,2例病灶周围血管受压推移;MRI上肿瘤表现为长T_1稍长T_2信号;7例增强扫描后病灶实质部分动脉期轻至中度强化,静脉期持续强化,中心坏死区无明显强化。结论原发性肝脏神经内分泌肿瘤具有一定的CT及MR影像特点,表现为肝内边界清晰的类圆形肿块,常伴中心坏死囊变及周围多发子灶,强化方式为延迟强化。Objective To investigate the CT and MRI findings of primary hepatic neuroendocrine carcinomas (PHNEC). Methods We identified eight patients diagnosed with PHNEC and analyzed their clinical features, pathological characteristics and images. Results Of the 8 cases, 2 were detected by MR and 5 by CT enhanced scan, only 1 by plain CT scan. 4 cases presented with single lesion and 4 cases with multiple lesions. All lesions on CT were low-density on plain scan with irregular lower-density areas in the center and clear edge, 3 cases showed surrounding multi-foci, 2 bigger lesions of these pushed the vascular to move aside. On MRI, the lesions showed low T 1WI signal and high T 2WI signal. 7 cases in artery phase showed tumor parenchyma mildly to moderately enhancement and continue enhanced in venous phase. The central lower-density area had no enhancement. Conclusion PHNEC has certain characteristics on CT and MRI images. It often shows intrahepatic mass with central necrosis and cyst, around by multiple foci and enhanced on the delayed phase.

关 键 词：肝脏 神经内分泌肿瘤 体层摄影术 X线计算机 磁共振成像 

分 类 号：R735.7[医药卫生—肿瘤] R445[医药卫生—临床医学]