恶性胃肠道间质瘤影像学特征及影响因素分析  

Imaging features and influencing factors of malignant gastrointestinal stromal tumors

作　　者：邓启付 林承露 汪全治[2] DENG Qifu;LIN Chenglu;WANG Quanzhi(Image Center,Second Peoplet's Hospital of Lu' an City,Luan 237008,P.R.China;Certer for Disease Contrel and Prevention of Liuan,Liuan 237000,P.R.China)

机构地区：[1]安徽省六安市第二人民医院影像中心,安徽六安237008 [2]安徽省六安市疾病预防控制中心,安徽六安237000

出　　处：《医学影像学杂志》2019年第4期626-630,共5页Journal of Medical Imaging

摘　　要：目的分析恶性胃肠道间质瘤影像学特征,探讨其影响因素。方法选择2009年8月～2017年9月在我院住院治疗,经CT和病理诊断为胃肠道间质瘤的患者,同时采用自制的调查问卷对患者进行问卷调查。根据肿瘤的性质分为良性组和恶性组,采用多因素logistic回归分析对恶性胃肠道间质瘤的影响因素进行分析。结果共有效调查78例患者,良性28例(35.9%),恶性50例(64.1%),肿瘤直径范围为0.5～26.7cm,多因素logistic回归分析显示肿瘤直径[OR (95%CI):28.13(6.21～250.84)]、肿瘤形态[OR (95%CI):(3.61～322.97)]、强化程度[(OR (95%CI):19.44(3.60～326.02)]以及强化方式[(OR (95%CI):19.74(1.48～264.17)]都是恶性胃肠道间质瘤的独立影响因素。结论肿瘤直径5cm及以上、肿瘤形态不规则、强化程度明显以及强化方式不均匀都是恶性胃肠道间质瘤的独立预测因素,患者出现这些CT征象可初步诊断为恶性胃肠道间质瘤。Objective To analyze the imaging features and influencing factors of malignant gastrointestinal stromal tumors to provide scientific basis for the prevention and early diagnosis and early treatment of malignant gastrointestinal stromal tumors. Methods Patients who were hospitalized in our hospital and diagnosed as gastrointestinal stromal tumor by CT and pathology from August 2009 to September 2017 were selected. The patients were investigated by self-made questionnaire. Patients were divided into benign and malignant groups according to the nature of the tumor. The multi-factor logistic regression was used to analyze the influence factors of malignant gastrointestinal stromal tumor. Results A total of 78 patients were effectively surveyed, 28 cases (35.9%) were benign, 50 cases (64.1%) were malignant, tumor diameter ranged from 0.5 to 26.7 cm. Multiariable logistic regression analysis revealed that the tumor diameter 〔(OR (95% CI): 28.13(6.21~250.84)〕, tumor shape 〔OR (95% CI):(3.61~322.97)〕, extent of strengthening 〔OR (95% CI): 19.44(3.60~326.02)〕, and way of strengthen 〔OR (95% CI): 19.74 (1.48~264.17)〕 were independent factors of malignant gastrointestinal stromal tumor. Conclusion Features that tumors diameter of 5 cm and above, tumor shape is irregular, obvious reinforcement and the reinforcement method is not uniform was independent predictors of malignant gastrointestinal stromal tumor. Therefore, patients can be primary diagnosed as malignant if had the above imaging features.

关 键 词：恶性 胃肠道间质瘤 体层摄影术 X线计算机 

分 类 号：R735[医药卫生—肿瘤] R814.42[医药卫生—临床医学]