重视真菌性眼内炎诊疗规范性  

Focus on the standardization of diagnosis and treatment of fungal endophthalmitis

作　　者：林晓峰[1] 袁敏而[1] Lin Xiaofeng;Yuan Miner(State Key Laboratory of Ophthalmology, Zhongshan Opthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China)

机构地区：[1]中山大学中山眼科中心眼科学国家重点实验室,广州510060

出　　处：《中华实验眼科杂志》2019年第5期321-325,共5页Chinese Journal Of Experimental Ophthalmology

基　　金：眼科学国家重点实验室专项经费项目(30306020240020130、3030902113030);广东省科技计划项目(2016A020215231).

摘　　要：真菌性眼内炎是一种损伤严重、预后差的眼部感染性疾病,它对眼部组织的损害程度与真菌的侵袭性、诊断是否及时和治疗是否规范有关。早期有效的干预对挽救视功能具有至关重要的作用。外源性感染和内源性感染在危险因素、致病菌和临床表现上均有不同的特征,须加以区分并在治疗上有所侧重,以合理选择抗真菌药物种类、给药方式、给药剂量或者手术方式,做到早期诊断及规范治疗。在真菌性眼内炎的治疗中,糖皮质激素的应用仍存在争议,治疗中应尽量避免局部或全身使用糖皮质激素。Fungal endophthalmitis is a kind of severe ocular infectious disease with poor prognosis. The damage degree of fungal endophthalmitis to ocular tissues is due to the fungi's destructivity delayed diagnosis and non standardized therapy. Early and proper intervention is crucial for saving visual function. There are different features of risk factors pathogens and clinical presentations in exogenous infection and endogenous infection. Different key points of theraputic approaches should be identified to achieve early diagnosis and effective treatment such as reasonably selecting the right type of antifungal drugs different ways of administration appropriate drug dose or surgical method. In the treatment of fungal endophthalmitis the application of glucocorticoid is controversial and the use of local or systemic glucocorticoid should be avoided as far as possible.

关 键 词：真菌性眼内炎 临床特征 诊断方法 抗真菌药物 

分 类 号：R771[医药卫生—眼科]