灌注指数与麻醉伤害趋势指数监测舒芬太尼对小儿腹腔镜手术伤害性刺激及麻醉效果的影响  

Effect of perfusion index and narcotrend index monitor on noxious stimulation and anesthesia in children after sufentanil general anesthesia

作　　者：刘峰[1] 李清军[1] LIU Feng;LI Qing-jun(Department of Anesthesiology,Yulin First Hospital,Shaanxi Province,Yulin 718000,China)

机构地区：[1]陕西省榆林市第一医院麻醉科,陕西榆林718000

出　　处：《河北医科大学学报》2019年第6期697-700,705,共5页Journal of Hebei Medical University

摘　　要：目的对比灌注指数(perfusion index,PI)与麻醉伤害趋势指数(narcotrend index,NTI)监测舒芬太尼对小儿腹腔镜手术全身麻醉后伤害性刺激及麻醉效果的影响。方法将140例行舒芬太尼全身麻醉腹腔镜疝手术患儿随机分为观察组和对照组,每组70例,观察组术中采用NTI监测,对照组采用PI监测,比较2组不同时点脑电双频指数(bispectral index,BIS)、收缩压(systolic blood pressure,SBP)、心率(heart rate,HR)和PI/NTI变化,应激反应阳性比和麻醉效果,比较2组不良反应发生率。结果 2组BIS、SBP和HR在时点间差异有统计学意义(P<0.05),在组间以及组间·时点间交互作用差异均无统计学意义(P>0.05);2组PI/NTI在组间、时点间以及组间·时点间交互作用差异均有统计学意义(P<0.05);观察组以PI/NTI判断应激反应阳性比显著高于对照组(P<0.05);2组不良反应率差异无统计学意义(P>0.05)。结论 PI和NTI均能较好地反映舒芬太尼在小儿全身麻醉期间的刺激性反应,但NTI更加敏感。Objective To explore the effect of perfusion index and narcotrend index monitor on noxious stimulation and anesthesia in children after sufentanil general anesthesia. Methods One hundred and forty patients undergoing laparoscopic surgery under general anesthesia for laparoscopic sucrose fentanyl treatment were randomly divided into observation group and control group with 70 cases in each group. The depth of anaesthesia was monitored by NTI in observation group and PI in control group to compare the changes in PI/NTI and anesthetic effects. Results BIS, SBP and HR during operation between the two groups had statistically difference(P<0.05), but the difference between the two groups and groups multiplied by different times were not statistically significant(P>0.05). PI/NTI between groups, different times, and groups multiplied by different times had statistically significant difference(P<0.05). The positive ratio judged by PI/NTI in observation group was significantly higher than control group(P<0.05). There were no significant difference in adverse reaction rates between the two groups(P>0.05).Conclusion Monitoring of perfusion index and narcotrend index can better reflect the stimulatory response of sufentanil during general anesthesia in children, but the narcotrend index is more sensitive.

关 键 词：腹腔镜 手术伤害性刺激 舒芬太尼 儿童 

分 类 号：R572[医药卫生—消化系统]