某院胃食管反流病诊疗现状分析  

Analysis of Diagnosis and Treatment of Gastroesophageal Reflux Disease in A Hospital

作　　者：陈惠弟 张亚坤[2] 许小鑫 曾莉莉[2] CHEN Huidi;ZHANG Yakun;XU Xiaoxin;ZENG Lili(Department of Gastroenterology,the 909 th Hospital/the Affiliated Dongnan Hospital of Xiamen University, Zhangzhou, Fujian Province (363000);Department of Pharmacy, the 909 th Hospital/the Affiliated Dongnan Hospital of Xiamen University, Zhangzhou, Fujian Province (363000))

机构地区：[1]联勤保障部队第九0九医院/厦门大学附属东南医院消化内科,363000 [2]联勤保障部队第九0九医院/厦门大学附属东南医院药学科,363000

出　　处：《胃肠病学》2019年第4期230-234,共5页Chinese Journal of Gastroenterology

基　　金：联勤保障部队第九〇九医院青年苗圃基金(15Y006)

摘　　要：背景:胃食管反流病(GERD)的发生率逐年上升且复发率高,但部分患者对质子泵抑制剂(PPI)的疗效欠佳。规范临床诊疗行为、提高患者用药依从性对提高GERD疗效非常重要。目的:了解某院GERD的诊疗现状。方法:随机抽取2017年1月-2018年3月联勤保障部队第九〇九医院/厦门大学附属东南医院GERD患者312例,对其PPI使用频数、初始治疗方案、PPI更换方案、PPI剂量、使用抗精神病药物、疗程、复查情况等进行回顾性分析。结果:近1/3的GERD患者接受抗精神病药物治疗,初始治疗方案主要为PPI+抗酸药和PPI+抗酸药+促胃肠动力药,51例治疗期间更换PPI,286例增加PPI剂量,54例按照基本标准的疗程持续治疗。结论:GERD治疗方案基本合理,但仍需进一步加强健康教育,提高患者的依从性,以提高GERD的疗效。Background: The incidence of gastroesophageal reflux disease( GERD) increased year by year and with a high risk of recurrence. The effect of proton pump inhibitors( PPIs) is not sufficient in some of the GERD patients. Aims: To investigate the status of diagnosis and treatment of GERD in a hospital. Methods: A total of 312 GERD patients from January 2017 to March 2018 at the 909 thHospital/the Affiliated Dongnan Hospital of Xiamen University were enrolled.Frequency of use of PPIs,initial therapy regimen,replacement of PPIs and dose of PPIs,use of antipsychotics,course of therapy and reexamination were retrospectively analyzed. Results: About 1/3 patients received the treatment of antipsychotics. The initial therapy was mainly PPIs + antacid or PPIs + antacid + prokinetics. PPIs was replaced in 51 patients,and the dose of PPIs was increased in 286 patients. And 54 patients received standard course of treatment.Conclusions: The treatment regimen of GERD is basically rational,however,health education should be strengthened and patient’s compliance be elevated for increasing the treatment efficacy of GERD.

关 键 词：胃食管反流 诊断 治疗 质子泵抑制剂 

分 类 号：R571[医药卫生—消化系统]