普萘洛尔治疗婴幼儿面部混合型血管瘤效果  

Efficacy of Propranolol in the Treatment of Mixed facial Hemangioma in Infants

作　　者：黄芳 HUANG Fang(Department of Pharmacy, Yichang City Maternal and Child Health Hospital, Yichang Hubei 443000, China)

机构地区：[1]湖北省宜昌市妇幼保健院药剂科,湖北宜昌443000

出　　处：《中国继续医学教育》2019年第14期153-155,共3页China Continuing Medical Education

摘　　要：目的探索普萘洛尔片治疗婴幼儿面部混合型血管瘤效果。方法选取2016年9月—2018年6月我院面部混合型血管瘤65例患儿作为研究对象。实施抽签分组方式,将其分为两组。对照组的32例患者进行泼尼松片治疗,观察组的33例患者进行普萘洛尔片治疗,对比两组谷丙转氨酶(ALT)、谷草转氨酶(AST)、肌酸激酶同工酶、肌酸激酶、总有效率、血流峰值、阻力系数。结果观察组ALT(33.86±2.46)U/L、AST(49.78±2.53)U/L、肌酸激酶同工酶(19.53±2.75)U/L、肌酸激酶(115.76±9.43)U/L、总有效率(96.97%)、血流峰值(21.41±3.26)cm/s、阻力系数(0.86±0.43)均优于对照组,差异具有统计学意义(P <0.05)。结论对面部混合型血管瘤婴幼儿实施普萘洛尔片治疗效果显著。Objective To explore the effect of propranolol tablets on facial mixed hemangioma in infants. Methods 65 children with mixed facial hemangioma in our hospital from September 2016 to June 2018 were selected as the study subjects. The method of lottery grouping is implemented and divided into two groups. 32 patients in the control group were treated with prednisone tablets. 33 patients in the observation group were treated with propranolol tablets. The ALT, AST, creatine kinase isoenzyme, creatine kinase, total effective rate, peak blood flow and resistance coefficient were compared between the two groups. Results The ALT(33.86±2.46) U/L, AST(49.78±2.53) U/L, creatine kinase isoenzyme(19.53±2.75) U/L, creatine kinase(115.76±9.43) U/L, the total effective rate(96.97%), peak blood flow(21.41±3.26) cm/s, resistance coefficient(0.86±0.43) of the observation group were all better than those of the control group, and the difference was statistically significant(P<0.05). Conclusion The effect of propranolol tablets on infants with facial mixed hemangioma is significant.

关 键 词：普萘洛尔片 婴幼儿 面部混合型血管瘤 血流峰值 总有效率 分析 

分 类 号：R739[医药卫生—肿瘤]