地佐辛联合瑞芬太尼对肝癌射频消融术患者麻醉效果分析  

Analysis of Anesthetic Effect of Radiochemotherapy for Hepatocarcinoma with Dezocine and Midazolam Combined with Remifentanil

作　　者：张宜林[1] 邵寒俏 ZHANG Yilin;SHAO Hanqiao(First Affiliated Hospital of Henan University of Science and Technology,Luoyang,471003)

机构地区：[1]河南科技大学第一附属医院,河南科技大学临床医学院,471003

出　　处：《实用癌症杂志》2019年第5期795-797,共3页The Practical Journal of Cancer

基　　金：河南省医学科技攻关计划项目(编号:201302018)

摘　　要：目的探讨地佐辛联合瑞芬太尼用于肝癌射频消融术患者麻醉的效果。方法选取应用射频消融术治疗的144例肝癌患者,随机分为对照组和实验组各72例,对照组患者给予咪达唑仑联合瑞芬太尼麻醉,实验组患者实施地佐辛联合瑞芬太尼麻醉,比较2组患者MAP、HR、VAS和并发症发生情况。结果 2组患者各时间段MAP和HR水平比较无统计学意义(P> 0. 05),术后1 h、术后2 h、术后3 h实验组患者VAS水平显著低于对照组,并发症发生率明显下降,差异具有统计学意义(P <0. 05)。结论针对肝癌射频消融术患者应用地佐辛与瑞芬太尼可提高麻醉效果,降低疼痛感及并发症发生率,值得推广应用。Objective To investigate the anesthesia of radiofrequency ablation of liver cancer with dezocine and midazolam combined with remifentanil. Methods One hundred and forty-four patients with liver cancer who had been treated with radiofrequency ablation were randomized.Patients in the control group were given anesthesia with midazolam and remifentanil,and patients in the experimental group were treated with diazepam.Symptoms of MAP,HR,VAS,and complications were compared between the two groups. Results There was no significant difference in MAP and HR levels between the two groups at each time ( P >0.05).The VAS levels in the experimental group were significantly lower than those in the control group at 1 hour,2 hours,and 3 hours after operation.The complication rate was significant.The difference was statistically significant ( P <0.05). Conclusion Dizocine and remifentanil for patients with radiofrequency ablation of liver cancer can improve the anesthetic effect,reduce the pain and the incidence of complications,and it is worth popularizing and applying.

关 键 词：地佐辛 咪达唑仑 瑞芬太尼 肝癌射频消融术 麻醉 

分 类 号：R735.7[医药卫生—肿瘤]