三维可视化重建技术改善肝细胞癌患者围手术期预后  

Three dimensional reconstruction technique improves perioperative prognosis in patients withhepatocellular carcinoma undergoing hepatectomy

作　　者：崔笑[1,2] 周大臣 张彬[1] 吴春利 汪雷[1] 潘树波[1] 陶然[1] 侯辉[1] Cui Xiao;Zhou Dachen;Zhang Bin;Wu Chunli;Wang Lei;Pan Shubo;Tao Ran;Hou Hui(Department of General Surgery, the Second Hospital of Anhui Medical University, Hefei 230601, China;Department of Surgery, University of Pittsburgh, 15213, USA)

机构地区：[1]安徽医科大学第二附属医院普通外科,合肥230601 [2]匹兹堡大学外科系,美国15213

出　　处：《中华普通外科杂志》2019年第5期425-427,共3页Chinese Journal of General Surgery

基　　金：安徽省高等学校自然科学基金资助项目(KJ2017A825);安徽省自然科学基金项目(1808085MH270);河南省高等学校重点科研项目(16A320007)。

摘　　要：目的比较术前三维可视化重建技术对肝细胞癌患者肝切除围手术期预后影响。方法回顾性分析2015-2017年期间因肝癌行肝部分切除患者58例临床资料,使用术前三维可视化重建患者23例,未三维重建者35例。比较使用该技术对围手术期主要临床指标的影响。结果使用组与未使用组患者术前临床病理特征差异无统计学意义。使用组患者手术时间更短(Z=-2.213,P=0.028),门脉阻断率和阻断时间更低或更短(χ^2=3.966,P=0.046;Z=-2.371,P=0.018),术中失血量更少(Z=-2.140,P=0.032)。术后发生23例Clavien-Dindo Ⅰ、Ⅱ级并发症,使用组发生率更低(χ^2=6.061,P=0.014)。结论使用三维可视化重建技术有助于改善肝癌患者围手术期预后。Objective To evaluate preoperative three dimensional (3D) reconstruction techniques in perioperative patients of hepatocellular carcinoma (HCC) undergoing hepatectomy.Methods Fifty-eight HCC patients who had undergone hepatectomy between 2015 and 2017 were enrolled.Twenty-three patients underwent hepatectomy based on preoperative 3D reconstruction techniques, while other thirty-five patients were without using it.Results No significant statistical difference was found in clincopathological parameters of patients preoperatively.The patients who underwent hepatectomy based on 3D reconstruction techniques had less operation time (Z=- 2.213 , P=0.028 ), hepatic inflow occlusion rate, time (χ^2=3.966 ,P=0.046;Z=2.371 , P=0.018 ) and blood loss (Z=2.140, P=0.032 ) during operation.Totally 23 postoperative complications occurred which were Clavien-Dindo classification grade Ⅰ or Ⅱ.More complications occurred in the not using 3D technique group (χ^2=6.061, P=0.014 ).Conclusion Preoperative 3D reconstruction technique improves the perioperative prognosis of hepatectomy in patients with hepatocellular carcinoma.

关 键 词：癌 肝细胞 肝切除术 成像 三维 

分 类 号：R735.7[医药卫生—肿瘤]