Porous graphene decorated silica as a new stationary phase for separation of sulfanilamide compounds in hydrophilic interaction chromatography  

作　　者：Lijun Song Haijuan Zhang Tianpei Cai Jia Chen Zhan Li Ming Guan Hongdeng Qiu 

机构地区：[1]Laboratory on Pollution Monitoring and Control, College of Chemistry and Chemical Engineering, Xinjiang Normal University [2]CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences

出　　处：《Chinese Chemical Letters》2019年第4期863-866,共4页中国化学快报（英文版）

基　　金：Financial supports from the National Natural Science Foundation of China (Nos. 21822407 and 21675164);the funds for Distinguished Young Scientists of Gansu (No. 1506RJDA281) are gratefully acknowledged

摘　　要：Porous graphene(PG) has potential applications in numerous fields because of the existence of nanopores in the plane. In this study, porous graphene decorated silica microspheres(Sil-PG) were successfully fabricated by assembling PG onto the silica particles surface in deep eutectic solvents(DESs).Experimental results demonstrate that this new stationary phase can facilitate the separation of six sulfonamides compounds in hydrophilic chromatographic conditions. The successful synthesis of the SilPG stationary phase provides a basis for the application of porous graphene-modified materials as the stationary phase for liquid chromatography, and offers the possibility to broaden the application of PG in the field of chromatography.Porous graphene(PG) has potential applications in numerous fields because of the existence of nanopores in the plane. In this study, porous graphene decorated silica microspheres(Sil-PG) were successfully fabricated by assembling PG onto the silica particles surface in deep eutectic solvents(DESs).Experimental results demonstrate that this new stationary phase can facilitate the separation of six sulfonamides compounds in hydrophilic chromatographic conditions. The successful synthesis of the SilPG stationary phase provides a basis for the application of porous graphene-modified materials as the stationary phase for liquid chromatography, and offers the possibility to broaden the application of PG in the field of chromatography.

关 键 词：POROUS GRAPHENE HYDROPHILIC interaction CHROMATOGRAPHY Stationary phase SULFONAMIDES Human serum samples 

分 类 号：O6[理学—化学]