CHROMATOGRAPHY

作品数：515被引量：855H指数：12
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A new green approach to synthesizing MIP-202@porous silica microspheres for positional isomer/enantiomer/hydrophilic separation
《Chinese Chemical Letters》2025年第1期501-505,共5页Zhefei Hu Jingwen Liao Jiawen Zhou Lulu Zhao Yanjuan Liu Yuefei Zhang Wei Chen Sheng Tang 
support of National Natural Science Foundation of China(No.21906124);Natural Science Foundation of Hubei Province(No.2017CFB220)。
Metal-organic frameworks(MOFs)with superior physicochemical properties have great potential for applications in chromatographic separation.However,currently popular methods for the synthesis of MOFbased silica composi...
关键词：Metal-organic framework Stationary phase Deep eutectic solvent Green chromatography High-performance liquid chromatography 
Antiparasitic Activity and Potential Active Compounds from Azadirachta Indica Revealed by Affinity Ultrafiltration Chromatography–Mass Spectrometry with Acetylcholinesterase and Lactate Dehydrogenases
《Journal of Analysis and Testing》2024年第4期403-414,共12页Minxia Fan Tojofaniry Fabien Rakotondrabe Guilin Chen Mingquan Guo 
the financial support from the Natural Science Foundation of Hubei Province(2021CFB263);the Opening Project of Hubei Key Laboratory of Purification and Application of Plant Anti-cancer Active Ingredients(HLPAI2023003)。
Azadirachta indica(A.indica)has traditionally been used to treat parasitic diseases,while its antiparasitic compounds and their mechanism remain ambiguous.Acetylcholinesterase(AChE)and lactate dehydrogenases(LDH)are t...
关键词：Azadirachta indica Parasitic diseases UF-LC-MS Molecular docking 
High throughput and rapid isolation of extracellular vesicles and exosomes with purity using size exclusion liquid chromatography
《Bioactive Materials》2024年第10期683-695,共13页Kshipra S.Kapoor Kristen Harris Kent A.Arian Lihua Ma Beatriz Schueng Zancanela Kaira A.Church Kathleen M.McAndrews Raghu Kalluri 
supported by NCI R35CA263815.KAC is supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under Award Numbers TL1TR003169 and UL1TR003167;The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health;We are grateful to Dr.Wenhua Guo for training KSK on cryogenic electron microscopy and Michelle Kirtley for assistance with serum samples.LM is thankful to the Shared Equipment Authority at Rice University for the support.Graphical figures in this work were created using BioRender.
Extracellular vesicles(EVs)have emerged as potential biomarkers for diagnosing a range of diseases without invasive procedures.Extracellular vesicles also offer advantages compared to synthetic vesicles for delivery o...
关键词：Extracellular vesicles Size exclusion-fast performance liquid CHROMATOGRAPHY Isolation methods 
Model-based risk assessment on dynamic control of twin-column continuous capture under feedstock variations
《Chinese Journal of Chemical Engineering》2024年第10期22-30,共9页Yu Fan Liang-Zhi Qiao Shan-Jing Yao Dong-Qiang Lin 
supported by the Zhejiang Key Science and Technology Project(2023C03116);National Natural Science Foundation of China(22078286);National Key Research and Development Program of China(2021YFE0113300).
Dynamic control is essential to guarantee the stable performance of continuous chromatography.AutoMAb dynamic control strategy has been developed to ensure a consistent protein load in twincolumn CaptureSMB continuous...
关键词：Continuous chromatography Process control Feedstock variations Mechanistic modeling PURIFICATION 
Graph convolutional network for axial concentration profiles prediction in simulated moving bed
《Chinese Journal of Chemical Engineering》2024年第9期270-280,共11页Can Ding Minglei Yang Yunmeng Zhao Wenli Du 
supported by the National Key Research and Development Program of China(2022YFB3305900);National Natural Science Foundation of China(62293501,62394343);the Shanghai Committee of Science and Technology,China(22DZ1101500);Major Program of Qingyuan Innovation Laboratory(00122002);Fundamental Research Funds for the Central Universities(222202417006);Shanghai AI Lab
The simulated moving bed(SMB)chromatographic separation is a continuous compound separation process based on the differences in adsorption capacity exhibited by distinct constituents of a mixture on the fluid phase an...
关键词：CHROMATOGRAPHY PREDICTION Operating variables Graph convolutional network OPTIMIZATION 
Chemical profiling of principle active and toxic constituents in herbs containing aristolochic acids被引量：1
《Chinese Herbal Medicines》2024年第2期293-300,共8页Lijun Yue Kaijun Yang Feng Jiang Shuai Dong Kang Yang Dan Zhu 
supported by the National Natural Science Foundation of China(No.81603076);Minzu University of China(No.2021MDYY53).
Objective:To clear the amounts of the principal active/toxic components in herbs containing aristolochic acids(HCAAs),which are still used as medicine and/or seasoning in many ethnic minority areas of China.Methods:In...
关键词：aristolactam aristolochic acids chemical profiling herbs containing aristolochic acids ultrahigh performance liquid chromatography-electrospray ionizationtandem mass spectrometry(UPLC-ESI-MS/MS) 
Chromatographic and mass spectroscopic guided discovery of Trichoderma peptaibiotics and their bioactivity
《Engineering Microbiology》2024年第2期62-76,共15页Adigo Setargie Chen Wang Liwen Zhang Yuquan Xu 
Peptaibiotics are linear or cyclic peptide antibiotics characterized by the non-proteinogenic amino acid,alpha-aminoisobutyric acid.They exhibit a wide range of bioactivity against various pathogens.This report presen...
关键词：CHROMATOGRAPHY peptaibiotics spectroscopy TRICHODERMA 
Simultaneous Determination of Trace Matrine and Oxymatrine Pesticide Residues in Tea by Magnetic Solid-Phase Extraction Coupled with Liquid Chromatography-Tandem Mass Spectrometry
《Journal of Analysis and Testing》2024年第2期245-250,共6页Hongmei Liu Yang Li Yangjiayi Xiang Hao Cao Yan Li 
supported by funds provided by the National Natural Science Foundation of China(21974024 and 22274025)。
We developed a magnetic solid-phase extraction method using Fe_(3)O_(4)@polydopamine(Fe_(3)O_(4)@PDA)as adsorbents,coupled with liquid chromatography-tandem mass spectrometry(LC-MS/MS),for the enrichment and quantific...
关键词：ADSORBENT CHROMATOGRAPHY adsorption 
Simultaneous purification of minor components in natural products using twin-column recycling chromatography with a step solvent gradient
《Chinese Journal of Chemical Engineering》2024年第5期212-219,共8页Guangxia Jin Yuxue Wu Feng Wei 
supported by the National Natural Science Foundation of China(22078281)。
The isolation of minor components from complex natural product matrices presents a significant challenge in the field of purification science due to their low concentrations and the presence of structurally similar co...
关键词：Solvent gradient Twin-column recycling chromatography PURIFICATION Minor component Natural products 
Gain deeper insights into traditional Chinese medicines using multidimensional chromatography combined with chemometric approaches被引量：1
《Chinese Herbal Medicines》2024年第1期27-41,共15页Xinyue Yang Pingping Zeng Jin Wen Chuanlin Wang Liangyuan Yao Min He 
This work is financially supported by the Hunan 2011 Collaborative Innovation Center of Chemical Engineering&Technology with Environmental Benignity and Effective Resource Utilization;Additional funding was provided by the Hunan Province Natural Science Fund(No.2020JJ4569 and 2023JJ60378);the Hunan Province College Students’Innovation and Entrepreneurship Training Program(No.S202110530044 and S202210530048).
Traditional Chinese medicines(TCMs)possess a rich historical background,unique theoretical framework,remarkable therapeutic efficacy,and abundant resources.However,the modernization and internationalization of TCMs ha...
关键词：CHEMOMETRICS multidimensional separation off-line two-dimensional liquid CHROMATOGRAPHY on-line two-dimensional liquid CHROMATOGRAPHY quality control traditional chinese medicines two-dimensional gas chromatography 
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