颈总动脉血流动力学参数在脑卒中颈内动脉颅内段病变的价值研究  

Study on the value of common carotid artery hemodynamics parameters in ICA intracranial lesions of stroke patients

作　　者：柳琳[1] 张峰[1] 管琳[1] 王竹梅[1] 吴宏赟[2] 殷颖[3] 郭良清[4] LIU Lin;ZHANG Feng;GUAN Lin(Special Inspection Section,the Affiliated Hospital of Shandong University of TCM,Jinan 250014,China)

机构地区：[1]山东中医药大学附属医院特检科,山东济南250014 [2]山东中医药大学附属医院脑病三科,山东济南250014 [3]山东中医药大学附属医院针灸科,山东济南250014 [4]山东中医药大学附属医院内分泌科,山东济南250014

出　　处：《中风与神经疾病杂志》2019年第5期443-445,共3页Journal of Apoplexy and Nervous Diseases

基　　金：山东省重点研发计划项目课题(No.2015GSF118163);山东省中医药科技发展计划项目(No.2015078)

摘　　要：目的探讨脑卒中患者单侧颈内动脉(ICA)颅内段病变与双侧颈总动脉(CCA)血流动力学相关参数的关系。方法选择脑卒中患者单侧颈内动脉颅内段病变且对侧同名动脉无狭窄或轻度狭窄者94例。测量其患侧及健侧颈内动脉和颈总动脉收缩期血流峰值(PSV)、舒张末期血流速度(EDV)、阻力指数(RI),以及颈总动脉血管内径(D)、血流量(BFV)。结果与脑卒中患者的健侧相比,患侧颈内动脉血流动力学参数PSV、EDV及RI均具有统计学意义(P<0.05)。患侧颈总动脉血流动力学参数BFV、EDV及RI均具有统计学意义(P<0.05)。颈内动脉PSV、EDV及RI与颈总动脉血流动力学的相关分析显示,颈内动脉的RI与颈总动脉的EDV、BFV呈负相关关系(P值<0.01),与颈总动脉的RI呈正相关关系(P均<0.05);颈内动脉的PSV、EDV与颈总动脉的EDV、BFV呈正相关(P<0.05),与颈总动脉的PSV、D无明显相关性(P>0.05)。结论颈总动脉的EDV、RI和BFV检测对脑卒中颈内动脉颅内段病变诊断具有较高价值,可以作为辅助诊断措施。Objective To explore the relationship between the parameters of bilateral carotid artery blood flow in patients with cerebral apoplexy patients with unilateral internal carotid artery.Methods In patients with cerebral apoplexy,there were 94 patients with unilateral internal carotid artery disease and no stenosis or mild stenosis.Lateral measuring the disease and the contralateral internal carotid artery(ICA) and common carotid artery(CCA) peak systolic blood flow(PSV),end-diastolic velocity(EDV),resistance index(RI),and carotid artery diameter(D),blood flow(BFV).Results Compared with the healthy side of cerebral apoplexy patients,PSV,EDV and RI were statistically significant(P<0.05).PSV,EDV and RI were both statistically significant(P<0.05).Internal carotid artery BFV,EDV,and RI is were associated with carotid artery blood flow mechanics analysis shows showed that the internal carotid artery RI and EDV of the common carotid arteries,negatively related BFV(P<0.01),and RI of the common carotid arteries were positively related(P<0.05);The PSV and EDV of the internal carotid artery were positively correlated with the EDV and BFV of the carotid artery(P<0.05),with no significant correlation with PSV and D of the general carotid artery(P > 0.05).Conclusion Detection of EDV,RI and BFV in common carotid artery has high value in diagnosing intracranial lesions of internal carotid artery and can be used as an auxiliary diagnostic measure.

关 键 词：颈总动脉 血流动力学 脑卒中 颈内动脉颅内段病变 颈动脉超声 

分 类 号：R743[医药卫生—神经病学与精神病学] R445.1[医药卫生—临床医学]