临床腋窝淋巴结阳性老年三阴性乳腺癌局部治疗策略  

Locoregional Treatment of Elderly Patients with Triple Negative Breast Cancer and Clinically Positive Axillary Lymph Nodes

作　　者：赵佳琳[1] 林燕[1] 王常珺[1] 徐颖[1] 孙强[1] ZHAO Jia-lin;LIN Yan;WANG Chang-jun;XU Ying;SUN Qiang(Department of Breast Surgery,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Pecking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院乳腺外科,北京100730

出　　处：《协和医学杂志》2019年第3期293-298,共6页Medical Journal of Peking Union Medical College Hospital

基　　金：北京市科学技术委员会重大专项科技计划(D161100000816005)

摘　　要：因老年乳腺癌患者多伴发基础疾病,在选择局部治疗方案时,除应考虑原发肿瘤本身因素外,还需评估患者重要器官功能及其对治疗的耐受能力。三阴性乳腺癌与其他亚型乳腺癌相比,主要表现为侵袭性强、预后不佳;而临床腋窝淋巴结阳性的老年三阴性乳腺癌患者,局部治疗的选择则更为棘手,对于此类特殊群体,尚需探索更为合理的个体化治疗方案。Elderly patients with breast cancer are often involved in complicated comorbidities. Besides the primary tumor, when formulating effective local therapeutic plans, clinicians should also evaluate the function of important organs and tolerance of elderly patients to the treatment. Compared with other subtypes, triple negative breast cancer(TNBC) is mainly characterized by strong invasiveness and a poor prognosis. The choice of locoregional treatment is more difficult for elderly patients with TNBC and clinically positive axillary lymph nodes. For such a special group, more reasonable individualized treatments need to be explored.

关 键 词：老年 三阴性乳腺癌 临床腋窝淋巴结阳性 手术 放疗 

分 类 号：R737.9[医药卫生—肿瘤]