年轻宫颈癌放疗中保留卵巢功能的研究进展  

The development for maintain the ovary function of young patients with radiotherapy of cervical carcinoma

作　　者：程晓龙[1] 刘吉平[1] Cheng Xiaolong;Liu Jiping(Radiation Physics, Zhejiang Cancer Hospital,Hangzhou,Zhejiang 310022,China)

机构地区：[1]浙江省肿瘤医院放射物理室,浙江杭州310022

出　　处：《医药前沿》2019年第13期9-10,共2页Journal of Frontiers of Medicine

摘　　要：为了明确宫颈癌放疗中卵巢功能与接受剂量间的关系,本文分别介绍了宫颈癌放疗中保留卵巢的必要性及可行性,卵巢功能的临床检测方法,着重归纳了卵巢功能损伤与其对应的剂量限值,并讨论了保卵巢的放疗技术,发现现有的研究存在样本量小、卵巢功能与放射剂量间的关系尚不统一的缺陷,导致临床医生在制定放疗计划时无明确的卵巢限值可以参考,进一步分析卵巢功能的相关因素,得出了通过大样本的研究来确定不同年龄段、有无化疗的患者卵巢功能与放射剂量间的关系是亟待解决的问题,实现个体化精确放疗是最终的目标.In order to make sure the relationship between the ovarian function and dose received during radiotherapy of cervical carcinoma, the necessity and feasibility of preserving ovarian function, the clinical detecting method of ovary function is introduced separately. The dose limit related to the ovary function is mainly summarized, and the radiotherapy technique of keeping ovarian function is discussed. The flaws of small sample size and the differs between ovary function with radiation dose are found in the existing studies, which results there is no clear ovarian dose limit can be consulted in the stage of formulating radiotherapy plan by clinicians. The related factors related to the ovary functions are analyzed further;realizing the individual predse radiotherapy is the final goal, and make sure the relationship between ovary function with radiation dose in the patient of different age stage, with or without chemotherapy by huge sample size study is the burning issue.

关 键 词：宫颈癌 卵巢 放疗 剂量 

分 类 号：R730.5[医药卫生—肿瘤]