急性缺血性脑卒中后患者认知功能障碍的相关因素研究  

Study on Related Factors of Cognitive Impairment in Patients after Acute Ischemic Stroke

作　　者：张洁[1] 李伟[1] 张亚红 王全保 韩红星[1] 刘运涌 付庆喜 王恺悦 高洪华 ZHANG Jie;LI Wei;ZHANG Ya-hong;WANG Quan-bao;HAN Hong-xing;LIU Yun-yong;FU Qing-xi;WANG Kai-yue;GAO Hong-hua(Department of Neurology, the Eleventh Clinical College, Linyi People's Hospital, Qingdao University , Linyi 276000, China)

机构地区：[1]青岛大学第十一临床学院-临沂市人民医院神经内科

出　　处：《中国临床神经科学》2019年第3期259-266,共8页Chinese Journal of Clinical Neurosciences

基　　金：山东省自然科学基金项目(编号:ZR2016HL16)

摘　　要：目的研究急性缺血性脑卒中后患者认知功能障碍(PSCI)发生的相关因素。方法收集住院急性期缺血性脑卒中患者288例,根据简易智力状态检查(MMSE)量表评分将入组患者分为PSCI组和非PSCI组,比较两组患者的临床资料,分析PSCI的可能相关影响因素。结果本研究PSCI的总发病率为53. 1%,Logistic回归分析显示,高龄、脑梗死病史、发病部位是PSCI发病的危险因素。结论急性缺血性脑卒中后PSCI常见,高龄、脑梗死病史、发病部位是PSCI发病的危险因素。Aim To investigate the influencing factors of cognitive impairment in patients after ischemic stroke. Methods 288 hospitalized patients with acute ischemic stroke were collected. According to the Mini-mental State Examination scale,the patients were divided into two groups: a post-stroke cognitive impairment( PSCI) group and a post-stroke non-cognitive impairment( nPSCI) group. The case data of the two groups were compared and the related factors of PSCI were analyzed. Results The overall incidence of PSCI in this study was 53. 1%. Logistic regression analysis showed that age,history of cerebral infarction and location of onset were risk factors for PSCI. Conclusion Cognitive impairment is common in patients with acute ischemic stroke. Age,history of cerebral infarction and location of onset are risk factors for cognitive impairment after stroke.

关 键 词：缺血性脑卒中 认知功能障碍 简易智力状态检查量表 

分 类 号：R743.3[医药卫生—神经病学与精神病学]