拜阿司匹林联合吡格雷双抗对短暂性脑缺血发作的疗效  

Therapeutic Effect of Combination of Aspirin and Clopidogrel on Transient Ischemic Attack

作　　者：林美容 麦汝娟 李世博[1] LIN Mei-rong;MAI Ru-juan;LI Shi-bo(Kaiping Center Hospital,Jiangmen 529300,Guangdong Province,China)

机构地区：[1]广东省江门市开平市中心医院,广东江门529300

出　　处：《罕少疾病杂志》2019年第2期18-19,94,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨对短暂性脑缺血发作患者联合使用拜阿司匹林、氯吡格雷双抗治疗的效果。方法依据治疗方案,将我院2016年8月至2017年8月就诊的78例短暂性脑缺血发作患者分为2组,39例单独以拜阿司匹林展开治疗为单抗组,39例以拜阿司匹林联合氯吡格雷双抗展开治疗为双抗组,对照两组疗效。结果单抗组30例显效,其中,23例无效,显效率为68.4%;双抗组36例显效,其中,6例无效,显效率为92.4%;双抗组优于单抗组,P<0.05。结论对于短暂性脑缺血发作的治疗,拜阿司匹林联合氯吡格雷展双抗开治疗效果更为优越,可减少再病发风险。Objective To investigate the combined use of aspirin in patients with transient ischemic attack,the effect of clopidogrel therapy.Methods double antibody therapy,78 cases of transient cerebral ischemia in our hospital from 2016 to 2017 8 months 8 months of onset were divided into 2 groups,39 cases with single aspirin expansion the treatment for 39 cases with monoclonal antibody group,aspirin and clopidogrel resistance start treatment for double double anti control group,the efficacy of the two groups.Results The monoclonal antibody group in 30 cases,among them,23 cases were invalid,the effective rate was 68.4%.Double resistance group was 36 cases,among them,6 cases had no effect,the effective rate was 92.4%.Double resistance group was better than that of P<0.05.monoclonal antibody group.Conclusion for the treatment of transient ischemic attack,aspirin combined with clopidogrel show double antibody treatment effect is superior to open,can reduce the disease risk.

关 键 词：短暂性 脑缺血 拜阿司匹林 氯吡格雷 

分 类 号：R743.31[医药卫生—神经病学与精神病学]