Association between timing of peritoneal dialysis initiation and mortality in end-stage renal disease  

作　　者：Yuan Peng Xiao Yang Wei Chen Xue-Qing Yu 

机构地区：[1]Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, China [2]Key Laboratory of Nephrology, National Health Commission and Guangdong Province, Guangzhou, Guangdong 510080, China

出　　处：《Chronic Diseases and Translational Medicine》2019年第1期37-43,共7页慢性疾病与转化医学（英文版）

基　　金：the National Key Research and Development Program (2016YFC0906101);the National Natural Science Foundation of China (81774069, 81570614);the Guangdong Science Foundation of China (2017A050503003, 2017B020227006);Foundation of Guangdong Key Laboratory of Nephrology (2014B030301023);the Guangdong Committee of Science and Technology (2014B020212020, 2017A050503003, 2017B020227006);the Guangzhou Municipal Programme of Science and Technology (2014Y2-00543, 201704020167).

摘　　要：Despite the widespread use of chronic dialysis for end-stage renal disease (ESRD), there is no consensus on the optimal timing of initiating renal replacement therapy. Over the past decade, a worldwide trend toward increasing glomerular filtration rate at the initiation of dialysis has been noted. However, available data indicate that early dialysis has no survival benefit or is harmful. Peritoneal dialysis (PD) is one alternative for ESRD and has potential survival factors different from those of hemodialysis. The association between the timing of PD initiation and survival is unclear. This review examines the effect of the timing of dialysis on clinical outcomes in PD patients.

关 键 词：PERITONEAL DIALYSIS (PD) INITIATION MORTALITY Glomerular FILTRATION rate (GFR) 

分 类 号：R[医药卫生]