盐酸吗啡静脉PCA在癌症晚期患者疼痛治疗中的临床效果及满意度影响分析  

Clinical Effect and Satisfaction Analysis of Morphine Hydrochloride PCA in the Treatment of Pain in Patients with Advanced Cancer

作　　者：刘方丽 LIU Fang-li(Department of Oncology Radiotherapy,Peony People's Hospital of Heze City,Heze,Shandong Province,274000 China)

机构地区：[1]菏泽市牡丹人民医院肿瘤科放疗病区

出　　处：《系统医学》2019年第8期142-144,共3页Systems Medicine

摘　　要：目的研究对癌症晚期患者采取盐酸吗啡静脉PCA进行疼痛治疗的临床效果,以及对患者满意度的影响。方法选取该院癌症晚期患者100例,选取时间为2015年7月—2016年8月,随机分成对照组和观察组,各50例,对照组采取盐酸吗啡肌注,观察组采取盐酸吗啡联合格雷司琼静脉PCA持续泵入治疗,记录并对比两组患者的临床治疗效果、患者满意度以及不良反应发生情况。结果经过治疗之后,观察组癌症晚期患者的生存时间为(243.78±35.26)d,下床活动时间为(1.59±0.94)h,VAS评分为(2.91±1.02)分,而对照组患者的生存时间、下床活动时间以及VAS评分分别为(92.16±20.31)d、(0.52±0.12)h、(7.56±2.59)分,两组相比差异有统计学意义(P<0.05)。观察组患者的满意度为96%,不良反应发生率为4%,而对照组患者的满意度和不良反应发生率分别为80%、18%,两组相比差异有统计学意义(P<0.05)。结论盐酸吗啡静脉PCA应用在癌症晚期患者疼痛治疗中,其止痛效果良好,可有效延长患者的生存时间,降低了不良反应发生率,提高了患者的满意度。Objective To study the clinical effect of morphine hydrochloride intravenous PCA on pain treatment in patients with advanced cancer,and the impact on patient satisfaction.Methods 100 patients with advanced cancer were selected from July 2015 to August 2016.They were randomly divided into control group and observation group,50 cases in each group.The control group received morphine hydrochloride intramuscular injection,and the observation group received morphine hydrochloride.Gravestron intravenous PCA was continuously pumped into the treatment,and the clinical treatment effect,patient satisfaction and adverse reactions of the two groups were recorded and compared.Results After treatment,the survival time of patients with advanced cancer in the observation group was (243.78±35.26) d,the time of getting out of bed was (1.59±0.94) h,and the VAS score was (2.91±1.02)points,while the survival time of the control group was lower.Bed activity time and VAS score were (92.16±20.31)d,(0.52±0.12)h,(7.56±2.59)points,and there was significant difference between the two groups(P<0.05).The satisfaction of patients in the observation group was 96%,and the incidence of adverse reactions was 4%.The satisfaction rate and adverse reaction rate of the control group were 80% and 18%,respectively.There was significant difference between the two groups(P<0.05).Conclusion Intravenous PCA administration of morphine hydrochloride is effective in the treatment of pain in patients with advanced cancer.It has a good analgesic effect,can effectively prolong the survival time of patients,reduce the incidence of adverse reactions,and improve patient satisfaction.

关 键 词：癌症晚期 盐酸吗啡 静脉PCA 疼痛治疗 临床效果 满意度 

分 类 号：R730.5[医药卫生—肿瘤]